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Article: Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Dvorzhak A; Semtner M; Faber DS; Grantyn R
J. Physiol. (Lond.), 2013

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neostriatum medium spiny neuron cell capacitance (pF) 79.7 79.7 (pF) Data Table
Neostriatum medium spiny neuron input resistance 59.2 59.2 (MΩ) Data Table
Neostriatum medium spiny neuron resting membrane potential (mV) -69.5 -69.5 (mV) Data Table
Neostriatum medium spiny neuron rheobase (pA) 189.6 189.6 (pA) Data Table

Report miscurated data

Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
PrepType in vitro
RecTemp 22.0 - 25.0
Species Mice
Strain Mouse, Transgenic
JxnPotential Not corrected
AnimalAge 78.0 ± 1.1
AnimalWeight 26.7 - 33.6
InternalSolution 5.0
ExternalSolution 5.0
internal_0_pH 7.2
internal_0_Mg 2.0
internal_0_Na 5.0
internal_0_K 150.0
internal_0_GTP 0.3
internal_0_ATP 2.0
internal_0_EGTA 5.0
internal_0_HEPES 25.0
internal_0_Cl 56.0
internal_0_Ca 0.5
external_0_pH 7.3
external_0_Mg 1.0
external_0_Na 151.25
external_0_K 2.0
external_0_Cl 133.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
16778 Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin. Dvorzhak A; Semtner M; Faber DS; Grantyn R J. Physiol. (Lond.) 2013 False 4 Shreejoy Tripathy, Brenna Li, Dmitry Tebaykin, 3
16780 Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin. Dvorzhak A; Semtner M; Faber DS; Grantyn R J. Physiol. (Lond.) 2013 False 2 0
16779 Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin. Dvorzhak A; Semtner M; Faber DS; Grantyn R J. Physiol. (Lond.) 2013 False 0 None
16781 Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin. Dvorzhak A; Semtner M; Faber DS; Grantyn R J. Physiol. (Lond.) 2013 False 0 None