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Article: Sleep loss alters synaptic and intrinsic neuronal properties in mouse prefrontal cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Winters BD; Huang YH; Dong Y; Krueger JM
Brain Res., 2011

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell first spike latency (ms) 406.89 ± 25.3 (22) 406.89 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell input resistance (MΩ) 223.79 ± 7.41 (22) 223.79 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell resting membrane potential (mV) -69.71 ± 1.76 (22) -69.71 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell rheobase (pA) 101.14 ± 5.06 (22) 101.14 (pA) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell spike amplitude (mV) 70.7 ± 1.27 (22) 70.7 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell spike half-width (ms) 0.98 ± 0.03 (22) 0.98 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell spike threshold (mV) -33.5 ± 0.93 (22) -33.5 (mV) Data Table

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Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
Strain C57BL
PrepType in vitro
AnimalAge 37.0 - 113.0
RecTemp 30.0
InternalSolution 5.0
ExternalSolution 5.0
JxnPotential Unreported
internal_0_pH 7.3
internal_0_Mg 2.5
internal_0_Na 3.55
internal_0_GTP 0.25
internal_0_ATP 2.5
internal_0_EGTA 0.4
internal_0_HEPES 20.0
internal_0_Cl 7.8
internal_0_Cs 117.0
external_0_Mg 1.2
external_0_Na 19.2
external_0_K 1.6
external_0_Cl 9.0
external_0_Ca 2.5
external_0_glucose 11.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
21653 Sleep loss alters synaptic and intrinsic neuronal properties in mouse prefrontal cortex. Winters BD; Huang YH; Dong Y; Krueger JM Brain Res. 2011 False 7 Shreejoy Tripathy, Brenna Li, Ryan Sefidpour, 6