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Article: Ketamine Administration During the Second Postnatal Week Alters Synaptic Properties of Fast-Spiking Interneurons in the Medial Prefrontal Cortex of Adult Mice.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Jeevakumar V; Kroener S
Cereb. Cortex, 2014

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex basket cell medial prefrontal cortex layer 5 fast-spiking parvalbumin positive GFP-expressing interneuron fast AHP amplitude (mV) 16.12 ± 1.13 (16) 16.12 (mV) Data Table
Neocortex basket cell medial prefrontal cortex layer 5 fast-spiking parvalbumin positive GFP-expressing interneuron input resistance (MΩ) 241.23 ± 24.8 (16) 241.23 (MΩ) Data Table
Neocortex basket cell medial prefrontal cortex layer 5 fast-spiking parvalbumin positive GFP-expressing interneuron spike amplitude (mV) 58.21 ± 3.51 (16) 58.21 (mV) Data Table
Neocortex basket cell medial prefrontal cortex layer 5 fast-spiking parvalbumin positive GFP-expressing interneuron spike half-width (ms) 0.76 ± 0.03 (16) 0.76 (ms) Data Table
Neocortex basket cell medial prefrontal cortex layer 5 fast-spiking parvalbumin positive GFP-expressing interneuron spike threshold (mV) -41.75 ± 1.61 (16) -41.75 (mV) Data Table

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Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
PrepType in vitro
ExternalSolution 5.0
external_1_Mg 1.0
external_1_Ca 2.0
external_1_Na 178.4
external_1_Cl 134.5
external_1_K 2.5
InternalSolution 5.0
internal_1_pH 7.2
internal_1_Na 10.0
internal_1_Cl 20.0
internal_1_K 130.0
Strain G42
Species Mice
JxnPotential Unreported
AnimalAge 70.0
RecTemp 20.0 - 24.0
internal_0_pH 7.2
internal_0_Mg 4.0
internal_0_Na 38.3
internal_0_K 130.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_HEPES 10.0
internal_0_Cl 20.0
external_0_Mg 1.0
external_0_Na 178.4
external_0_K 2.5
external_0_Cl 134.5
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
36300 Ketamine Administration During the Second Postnatal Week Alters Synaptic Properties of Fast-Spiking Interneurons in the Medial Prefrontal Cortex of Adult Mice. Jeevakumar V; Kroener S Cereb. Cortex 2014 False 5 Shreejoy Tripathy, Kerrie Tsigounis, Ryan Sefidpour, Athanasios Kritharis, 2