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Article: Differential slow inactivation and use-dependent inhibition of Nav1.8 channels contribute to distinct firing properties in IB4+ and IB4- DRG neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Choi JS; Dib-Hajj SD; Waxman SG
J. Neurophysiol., 2007

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Dorsal root ganglion cell Isolectin B(4)-positive nonpeptidergic neurons cell capacitance (pF) 26.1 ± 1.5 26.1 (pF) Data Table
Dorsal root ganglion cell Isolectin B(4)-negative peptidergic neurons cell capacitance (pF) 25.9 ± 1.2 25.9 (pF) Data Table
Dorsal root ganglion cell Isolectin B(4)-positive nonpeptidergic neurons first spike latency (ms) 226.1 ± 27.0 226.1 (ms) Data Table
Dorsal root ganglion cell Isolectin B(4)-negative peptidergic neurons first spike latency (ms) 104.8 ± 19.4 104.8 (ms) Data Table
Dorsal root ganglion cell Isolectin B(4)-negative peptidergic neurons input resistance (MΩ) 667.5 ± 111.0 667.5 (MΩ) Data Table
Dorsal root ganglion cell Isolectin B(4)-positive nonpeptidergic neurons input resistance (MΩ) 491.8 ± 79.7 491.8 (MΩ) Data Table
Dorsal root ganglion cell Isolectin B(4)-positive nonpeptidergic neurons resting membrane potential (mV) -59.9 ± 1.9 -59.9 (mV) Data Table
Dorsal root ganglion cell Isolectin B(4)-negative peptidergic neurons resting membrane potential (mV) -48.9 ± 1.6 -48.9 (mV) Data Table
Dorsal root ganglion cell Isolectin B(4)-positive nonpeptidergic neurons rheobase (pA) 56.8 ± 1.1 56.8 (pA) Data Table
Dorsal root ganglion cell Isolectin B(4)-negative peptidergic neurons rheobase (pA) 58.2 ± 2.5 58.2 (pA) Data Table
Dorsal root ganglion cell Isolectin B(4)-positive nonpeptidergic neurons spike peak (mV) 4.0 4.0 (mV) Data Table
Dorsal root ganglion cell Isolectin B(4)-negative peptidergic neurons spike peak (mV) 4.0 4.0 (mV) Data Table
Dorsal root ganglion cell Isolectin B(4)-positive nonpeptidergic neurons spike threshold (mV) 2.3 ± 0.2 -- Data Table
Dorsal root ganglion cell Isolectin B(4)-negative peptidergic neurons spike threshold (mV) 1.8 ± 0.1 -- Data Table

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Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
Strain Sprague-Dawley

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
408 Differential slow inactivation and use-dependent inhibition of Nav1.8 channels contribute to distinct firing properties in IB4+ and IB4- DRG neurons. Choi JS; Dib-Hajj SD; Waxman SG J. Neurophysiol. 2007 False 8 Hannah Sangra, 1