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Article: Electrophysiological Abnormalities in Both Axotomized and Nonaxotomized Pyramidal Neurons following Mild Traumatic Brain Injury.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Greer JE; Povlishock JT; Jacobs KM
J. Neurosci., 2012

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Regular spiking, Thy1-expressing layer V pyramidal neurons of somatosensory cortex input resistance (MΩ) 86.4 ± 8.6 86.4 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Regular spiking, Thy1-expressing layer V pyramidal neurons of somatosensory cortex input resistance (MΩ) 87.2 ± 7.2 87.2 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Regular spiking, Thy1-expressing layer V pyramidal neurons of somatosensory cortex membrane time constant (ms) 15.7 ± 0.9 15.7 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Regular spiking, Thy1-expressing layer V pyramidal neurons of somatosensory cortex membrane time constant (ms) 17.1 ± 1.5 17.1 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Regular spiking, Thy1-expressing layer V pyramidal neurons of somatosensory cortex resting membrane potential (mV) -60.2 ± 0.4 (15) -60.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Regular spiking, Thy1-expressing layer V pyramidal neurons of somatosensory cortex resting membrane potential (mV) -60.1 ± 0.3 (23) -60.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Regular spiking, Thy1-expressing layer V pyramidal neurons of somatosensory cortex spike peak (mV) 50.4 ± 1.7 50.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Regular spiking, Thy1-expressing layer V pyramidal neurons of somatosensory cortex spike rise time (ms) 0.25 ± 0.02 0.25 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Regular spiking, Thy1-expressing layer V pyramidal neurons of somatosensory cortex spike threshold (mV) -37.6 ± 0.9 -37.6 (mV) Data Table

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Metadata values

Experimental condition Value
AnimalAge 49.0 - 56.0
PrepType in vitro
ElectrodeType Patch-clamp
Species Mice
RecTemp 30.0 - 32.0
Strain Thy1-YFP
InternalSolution 5.0
ExternalSolution 5.0
JxnPotential Unreported
internal_0_pH 7.3
internal_0_Na 6.3
internal_0_K 140.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_EGTA 4.0
internal_0_HEPES 10.0
internal_0_Cl 72.0
external_0_pH 7.4
external_0_Mg 2.0
external_0_Na 153.25
external_0_K 5.0
external_0_Cl 139.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
14294 Electrophysiological Abnormalities in Both Axotomized and Nonaxotomized Pyramidal Neurons following Mild Traumatic Brain Injury. Greer JE; Povlishock JT; Jacobs KM J. Neurosci. 2012 False 6 Shreejoy Tripathy, 3