NeuroElectro Publications

Article: Membrane properties of striatal direct and indirect pathway neurons in mouse and rat slices and their modulation by dopamine.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Planert H; Berger TK; Silberberg G
PLoS ONE, 2013

Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Neostriatum medium spiny neuron	Striatum Drd1-expressing striatonigral direct pathway medium spiny neuron	FI slope (Hz/pA)	0.16	160.0 (Hz/nA)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing striatopallidal indirect pathway medium spiny neuron	FI slope (Hz/pA)	0.21	210.0 (Hz/nA)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing striatopallidal indirect pathway medium spiny neuron	input resistance (MΩ)	164.2	164.2 (MΩ)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1-expressing striatonigral direct pathway medium spiny neuron	input resistance (MΩ)	138.39	138.39 (MΩ)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing striatopallidal indirect pathway medium spiny neuron	membrane time constant (ms)	13.85	13.85 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1-expressing striatonigral direct pathway medium spiny neuron	membrane time constant (ms)	12.98	12.98 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing striatopallidal indirect pathway medium spiny neuron	resting membrane potential (mV)	-64.87	-64.87 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1-expressing striatonigral direct pathway medium spiny neuron	resting membrane potential (mV)	-67.67	-67.67 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1-expressing striatonigral direct pathway medium spiny neuron	rheobase (pA)	191.42	191.42 (pA)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing striatopallidal indirect pathway medium spiny neuron	rheobase (pA)	139.1	139.1 (pA)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1-expressing striatonigral direct pathway medium spiny neuron	spike amplitude (mV)	82.23	82.23 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing striatopallidal indirect pathway medium spiny neuron	spike amplitude (mV)	82.55	82.55 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing striatopallidal indirect pathway medium spiny neuron	spike half-width (ms)	1.1	1.1 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1-expressing striatonigral direct pathway medium spiny neuron	spike half-width (ms)	1.16	1.16 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1-expressing striatonigral direct pathway medium spiny neuron	spike threshold (mV)	-42.42	-42.42 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing striatopallidal indirect pathway medium spiny neuron	spike threshold (mV)	-41.94	-41.94 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1-expressing striatonigral direct pathway medium spiny neuron	spike width (ms)	3.11	3.11 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing striatopallidal indirect pathway medium spiny neuron	spike width (ms)	2.99	2.99 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1a-expressing medium spiny neuron	FI slope (Hz/pA)	0.12	120.0 (Hz/nA)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing medium spiny neuron	FI slope (Hz/pA)	0.15	150.0 (Hz/nA)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing medium spiny neuron	input resistance (MΩ)	96.44	96.44 (MΩ)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1a-expressing medium spiny neuron	input resistance (MΩ)	85.26	85.26 (MΩ)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing medium spiny neuron	membrane time constant (ms)	5.98	5.98 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1a-expressing medium spiny neuron	membrane time constant (ms)	5.16	5.16 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing medium spiny neuron	resting membrane potential (mV)	-78.91	-78.91 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1a-expressing medium spiny neuron	resting membrane potential (mV)	-78.65	-78.65 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1a-expressing medium spiny neuron	rheobase (pA)	355.39	355.39 (pA)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing medium spiny neuron	rheobase (pA)	268.74	268.74 (pA)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1a-expressing medium spiny neuron	spike amplitude (mV)	78.5	78.5 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing medium spiny neuron	spike amplitude (mV)	78.77	78.77 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing medium spiny neuron	spike half-width (ms)	0.75	0.75 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1a-expressing medium spiny neuron	spike half-width (ms)	0.77	0.77 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1a-expressing medium spiny neuron	spike threshold (mV)	-42.73	-42.73 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing medium spiny neuron	spike threshold (mV)	-44.29	-44.29 (mV)	Data Table
Neostriatum medium spiny neuron	Striatum Drd1a-expressing medium spiny neuron	spike width (ms)	1.83	1.83 (ms)	Data Table
Neostriatum medium spiny neuron	Striatum Drd2-expressing medium spiny neuron	spike width (ms)	1.75	1.75 (ms)	Data Table

Metadata values

Experimental condition	Value
Species	Rats
ElectrodeType	Patch-clamp
RecTemp	34.0 - 35.0
PrepType	in vitro
JxnPotential	Not corrected
ExternalSolution	5.0
InternalSolution	5.0
Strain	Rats, Sprague-Dawley
AnimalAge	14.0 - 19.0
Species	Mice
Strain	Mouse, Transgenic
internal_0_Mg	4.0
internal_0_Na	10.0
internal_0_K	135.0
internal_0_GTP	0.3
internal_0_ATP	4.0
internal_0_HEPES	10.0
internal_0_Cl	30.0
external_0_Mg	1.0
external_0_Na	151.25
external_0_K	2.5
external_0_Cl	133.5
external_0_Ca	2.0
external_0_glucose	25.0

Data table listing

Data Table	Article Title	Authors	Journal	Year	Table needs expert?	Ephys table mentions	Curated by	Times validated
33325	Membrane properties of striatal direct and indirect pathway neurons in mouse and rat slices and their modulation by dopamine.	Planert H; Berger TK; Silberberg G	PLoS ONE	2013	False	9	Shreejoy Tripathy, James liu,	3
33326	Membrane properties of striatal direct and indirect pathway neurons in mouse and rat slices and their modulation by dopamine.	Planert H; Berger TK; Silberberg G	PLoS ONE	2013	False	9	Shreejoy Tripathy, James liu,	3
33327	Membrane properties of striatal direct and indirect pathway neurons in mouse and rat slices and their modulation by dopamine.	Planert H; Berger TK; Silberberg G	PLoS ONE	2013	False	6		0
33328	Membrane properties of striatal direct and indirect pathway neurons in mouse and rat slices and their modulation by dopamine.	Planert H; Berger TK; Silberberg G	PLoS ONE	2013	False	6		0
33329	Membrane properties of striatal direct and indirect pathway neurons in mouse and rat slices and their modulation by dopamine.	Planert H; Berger TK; Silberberg G	PLoS ONE	2013	False	6		0