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Article: COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B
J. Neurosci., 2015

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex interneuron deep barrel cortex GABAergic interneuron cell capacitance (pF) 67.5 ± 4.5 (66) 67.5 (pF) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron input resistance (MΩ) 526.0 ± 29.0 (66) 526.0 (MΩ) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron membrane time constant (ms) 32.2 ± 2.1 (66) 32.2 (ms) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron resting membrane potential (mV) -59.8 ± 0.8 (66) -59.8 (mV) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron sag ratio 9.6 ± 1.1 (66) 0.096 (ratio) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell cell capacitance (pF) 122.4 ± 5.8 (24) 122.4 (pF) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell input resistance (MΩ) 277.0 ± 30.0 (24) 277.0 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell membrane time constant (ms) 32.2 ± 2.6 (24) 32.2 (ms) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell resting membrane potential (mV) -69.7 ± 1.8 (24) -69.7 (mV) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell sag ratio 7.1 ± 1.4 (24) 0.071 (ratio) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron ADP amplitude 1.9 ± 0.3 (66) 1.9 (mV) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron ADP duration 4.4 ± 0.7 (66) 4.4 (ms) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron AHP amplitude -15.2 ± 0.6 (66) 15.2 (mV) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron AHP duration 3.8 ± 0.2 (66) 3.8 (ms) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron spike amplitude (mV) 89.2 ± 1.4 (66) 89.2 (mV) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron spike width (ms) 0.7 ± 0.1 (66) 0.7 (ms) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell ADP amplitude 24.0 (24) 24.0 (mV) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell ADP duration 24.0 (24) 24.0 (ms) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell AHP amplitude -5.9 ± 0.6 (24) 5.9 (mV) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell AHP duration 7.0 ± 0.6 (24) 7.0 (ms) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell spike amplitude (mV) 96.6 ± 2.3 (24) 96.6 (mV) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell spike width (ms) 1.3 ± 0.1 (24) 1.3 (ms) Data Table
Neocortex interneuron deep barrel cortex GABAergic interneuron maximum firing rate (Hz) 92.0 ± 7.5 (66) 92.0 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 barrel cortex layer 2-3 pyramidal cell maximum firing rate (Hz) 45.6 ± 2.8 (24) 45.6 (Hz) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
RecTemp 27.0 ± 0.5
PrepType in vitro
JxnPotential Not corrected
InternalSolution 5.0
ExternalSolution 5.0
Strain Rats, Wistar
AnimalAge 17.0 ± 0.1
internal_0_pH 7.2
internal_0_Mg 3.0
internal_0_K 144.0
internal_0_EGTA 0.5
internal_0_HEPES 10.0
internal_0_Cl 6.0
external_0_Mg 1.0
external_0_Na 153.25
external_0_K 2.5
external_0_Cl 134.5
external_0_Ca 2.0
external_0_glucose 10.0
external_0_kynur 1.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
47301 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B J. Neurosci. 2015 True 6 Shreejoy Tripathy, Brenna Li, Athanasios Kritharis, 1
47300 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B J. Neurosci. 2015 False 5 Shreejoy Tripathy, Athanasios Kritharis, 1
47293 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B J. Neurosci. 2015 False 1 0
47299 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B J. Neurosci. 2015 False 1 0
47302 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B J. Neurosci. 2015 True 1 Shreejoy Tripathy, Ryan Sefidpour, Athanasios Kritharis, 1
47294 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B J. Neurosci. 2015 False 0 None
47295 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B J. Neurosci. 2015 False 0 None
47296 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B J. Neurosci. 2015 False 0 None
47297 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B J. Neurosci. 2015 False 0 None
47298 COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex. Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B J. Neurosci. 2015 False 0 None