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Article: Oxidative stress induced by cumene hydroperoxide evokes changes in neuronal excitability of rat motor cortex neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Pardillo-Díaz R; Carrascal L; Ayala A; Nunez-Abades P
Neuroscience, 2015

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 pyramidal cell FI slope 44.1 ± 5.9 (30) 44.1 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 pyramidal cell input resistance (MΩ) 188.4 ± 19.0 (30) 188.4 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 pyramidal cell maximum firing rate 29.3 ± 3.5 (30) 29.3 (Hz) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 pyramidal cell resting membrane potential (mV) -70.7 ± 1.3 (30) -70.7 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 pyramidal cell rheobase (pA) 176.5 ± 22.4 (30) 176.5 (pA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 pyramidal cell spike amplitude from resting (mV) 118.0 ± 0.5 (30) 118.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 pyramidal cell spike half-width (ms) 1.44 ± 0.02 (30) 1.44 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 pyramidal cell spike threshold (mV) -39.4 ± 1.6 (30) -39.4 (mV) Data Table

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Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
Strain Rats, Wistar
PrepType in vitro
InternalSolution 5.0
ExternalSolution 5.0
Species Rats
JxnPotential Unreported
AnimalAge 20.0 - 40.0
RecTemp 33.0 ± 1.0
internal_0_pH 7.3
internal_0_Mg 2.0
internal_0_Na 20.3
internal_0_K 130.0
internal_0_GTP 0.3
internal_0_ATP 2.0
internal_0_EGTA 0.1
internal_0_HEPES 10.0
internal_0_Cl 10.0
external_0_Mg 2.0
external_0_Na 154.5
external_0_K 2.0
external_0_Cl 136.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
47963 Oxidative stress induced by cumene hydroperoxide evokes changes in neuronal excitability of rat motor cortex neurons. Pardillo-Díaz R; Carrascal L; Ayala A; Nunez-Abades P Neuroscience 2015 False 8 Brenna Li, Ryan Sefidpour, 1