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Article: Responses of deep entorhinal cortex are epileptiform in an electrogenic rat model of chronic temporal lobe epilepsy.

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Fountain NB; Bear J; Bertram EH; Lothman EW
J. Neurophysiol., 1998


Table 3.

IPSP characteristics using the monosynaptic IPSP protocol

Control Epileptic
n 45 5
GABAA maximum amplitude, mV 6.5 ± 0.64 7.7 ± 1.49
GABAA TTP, ms 26 ± 3.8 16.8 ± 2.78
GABAA Vr, mV −70 ± 1.32 −69 ± 0.67
GABAB maximum amplitude, mV 3.5 ± 0.39 2.1 ± 1.05
GABAB TTP,* ms 118 ± 4.46 91 ± 9.24
GABAB Vr, mV −86 ± 2.25 −82 ± 1.4

  • Values are means ± SE. No differences between epileptic and control groups are statistically different (P > 0.05) compared by ANOVA. TTP, time-to-peak amplitude; Vr, reverse potential.

  • F3-150 GABAA and GABAB are early and late IPSPs, respectively.


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