Table 1.
Effect of adding gh on different cell properties and responses to current injections and sound stimuli in vivo
| Cell Properties | No Ih | Ih |
|---|---|---|
| Vm, mV | −66.5 ± 1.5 (13) | −62.7 ± 1.2** |
| Rm, MΩ | 134 ± 11.3 (19) | 78 ± 5.6** |
| Spike threshold, mV | −50.4 ± 1.5 (10) | −50.1 ± 1.5 |
| Relative spike threshold, mV | 14.4 ± 1.8 (10) | 10.4 ± 1.3** |
| Percentage depolarizing sag | 2.1 ± 0.4 (19) | 24 ± 1.0** |
| τfast depolarizing sag, ms | — | 32.7 ± 0.7 (19) |
| Amplitude τfast, mV | — | −4.2 ± 0.09 (19) |
| τslow depolarizing sag, ms | — | 250.3 ± 5.8 (19) |
| Amplitude τslow, mV | — | −2.6 ± 0.07 (19) |
| Current injections | ||
| Depolarizing summation index, % | 146 ± 19 (14) | 77 ± 10* |
| Peak - trough amplitude, mV | 2.04 ± 0.05 (14) | 2.10 ± 0.06** |
| Hyperpolarizing summation index, % | 115 ± 20 (14) | 58 ± 6* |
| Peak - trough amplitude, mV | 2.06 ± 0.05 (14) | 2.18 ± 0.06** |
| Tone response, 50 ms | ||
| Max EPSP depolarization, mV | −54.1 ± 1.6 (13) | −52.3 ± 1.4** |
| EPSP amplitude, mV | 12.5 ± 1.6 (13) | 10.4 ± 1.5** |
| EPSP full width at half maximum, ms | 41.0 ± 1.9 (13) | 37.9 ± 1.8* |
| Tone response after current injection | ||
| Max depolarization, mV | −54.0 ± 1.4 (13) | −52.8 ± 1.4** |
| EPSP amplitude, mV | 12.6 ± 1.6 (13) | 10.0 ± 1.5** |
| Max difference with no injection, mV | 0.03 ± 0.36 (13) | −0.42 ± 0.21 |
| SAM tones | ||
| Modulated potential, mV | 2.29 ± 0.39 (13) | 2.23 ± 0.37 |
| R (vector strength) | 0.46 ± 0.13 (4) | 0.37 ± 0.10 |
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Values represent means ± SE, the number of cells is between parentheses.
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↵ One asterisk indicates a significant difference of P < 0.05;
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↵** , P < 0.01. Max difference with no injection refers to the difference in the maximal depolarization in response to a tone with or without a preceding depolarization. EPSP, excitatory postsynaptic potential; SAM, sinusoidal amplitude modulated.