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Article: Enhanced function of prefrontal serotonin 5-HT(2) receptors in a rat model of psychiatric vulnerability.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Benekareddy M; Goodfellow NM; Lambe EK; Vaidya VA J. Neurosci., 2010
Table 2.
Layer V pyramidal neurons from ES animals are significantly more depolarized, but display no change in spike amplitude or input resistance
| Control (n = 74) | Early stress (n = 87) | p value | |
|---|---|---|---|
| Resting membrane potential (mV) | −82.4 ± 0.6 | −80.5 ± 0.6 | 0.03 |
| Spike amplitude (mV) | 86.4 ± 0.7 | 85.8 ± 0.8 | 0.5 |
| Input resistance (MΩ) | 102.2 ± 6.3 | 99.9 ± 5.1 | 0.7 |
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Values are shown as mean ± SEM and were compared with Student's unpaired t test.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Neocortex pyramidal cell layer 5-6 | prefrontal cortex layer 5 pyramidal neuron | resting membrane potential (mV) | -82.4 ± 0.6 (74) | -82.4 (mV) | Data Table |
| Neocortex pyramidal cell layer 5-6 | prefrontal cortex layer 5 pyramidal neuron | spike amplitude (mV) | 86.4 ± 0.7 (74) | 86.4 (mV) | Data Table |
| Neocortex pyramidal cell layer 5-6 | prefrontal cortex layer 5 pyramidal neuron | input resistance (MΩ) | 102.2 ± 6.3 (74) | 102.2 (MΩ) | Data Table |