Article: Changes in membrane excitability and potassium currents in sensitized dorsal horn neurons of mice pups.

Table 1.

Synaptic and electrophysiological properties of current clamp recorded dorsal horn neurons

	Control	Carrageenan-treated 20 h	NMDA-treated	Carragenan-treated 1 h
Synaptic properties
Spontaneous firing (n)	9/19	14/16^*	4/9	5/9
A-fiber intensity
n	16	15	7	9
EPSP latency (ms)	4.6 ± 0.4	3.3 ± 0.2^**	3.9 ± 0.7	3.2 ± 0.2^*
Spike latency (ms)	8.9 ± 1.1	5.2 ± 0.5^**	6.2 ± 1.2	5.5 ± 1.5^*
Rise rate (mV/ms)	5.8 ± 1.0	11.9 ± 1.7^**	12.1 ± 2.6^*	14.6 ± 2.4^**
C-fiber intensity
n	14	12	3	5
EPSP latency (ms)	4.1 ± 0.2	3.3 ± 0.2^*	3.0 ± 0.6	2.9 ± 0.2^**
Spike latency (ms)	6.7 ± 0.7	4.7 ± 0.4^*	5.8 ± 2.2	3.8 ± 0.3^*
Rise rate (mV/ms)	8.7 ± 1.4	17.4 ± 2.7^*	12.0 ± 6.7	17.1 ± 2.7^*
Electrophysiological properties
n	19	16	9	9
RPM (mV)	−55.7 ± 0.8	−56.9 ± 0.8	−57.3 ± 1.9	−58.4 ± 1.2
R_in (MΩ)	355 ± 20	327 ± 30	348 ± 35	426 ± 33
AP-A (mV)	65 ± 2	71 ± 3	72 ± 3	63 ± 3
AP-T (mV)	−39.7 ± 0.7	−39.7 ± 0.6	−39.6 ± 1.0	−44.7 ± 1.1^***
Tonic firing (n)	18	13	8	8
Phasic firing (n)	1	3	1	1

↵Quantifications of synaptic properties were made on responses to A- and C-fiber intensity stimuli (200 μs and 20 μA, and 200 μs and 200 μA, respectively). Values are means ± SEM. Asterisks mark significant differences with control (*p < 0.05;
↵**p < 0.01;
↵***p < 0.001, Mann–Whitney test or Fisher exact test). n, Number of observations; RMP, resting membrane potential; R_in, input resistance; AP-A, action potential amplitude; AP-T, action potential threshold.

Inferred neuron-electrophysiology data values

Neuron Type	Ephys Prop	Extracted Value	Standardized Value	Content Source
Dorsal root ganglion cell	resting membrane potential (mV)	-55.7 ± 0.8 (19)	-55.7 (mV)	Data Table
Dorsal root ganglion cell	input resistance (MΩ)	355.0 ± 20.0 (19)	355.0 (MΩ)	Data Table
Dorsal root ganglion cell	spike amplitude (mV)	65.0 ± 2.0 (19)	65.0 (mV)	Data Table
Dorsal root ganglion cell	spike threshold (mV)	-39.7 ± 0.7 (19)	-39.7 (mV)	Data Table