Total numbers of neurones are indicated. For SPNs, the second number indicates spontaneously active neurones included in spiking properties and spike waveform measurements. Data are means ± SD across neurones.
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Article: Enhanced high-frequency membrane potential fluctuations control spike output in striatal fast-spiking interneurones in vivo.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Schulz JM; Pitcher TL; Savanthrapadian S; Wickens JR; Oswald MJ; Reynolds JN J. Physiol. (Lond.), 2011
| Response to current steps | FSIs (n= 9) | SPNs (n= 90; 74) | CINs (n= 12) |
|---|---|---|---|
| Input resistance (MΩ) | 31.2 ± 14.0 | 34.0 ± 11.9 | 47.8 ± 11.4 |
| Membrane time constant (ms) | 3.1 ± 1.1 | 3.8 ± 1.5 | 7.8 ± 1.7 |
| Cell capacitance (pF) | 115.9 ± 51.1 | 122.6 ± 54.4 | 157.0 ± 48.7 |
| Rheobase current (nA) | 0.89 ± 0.32 | 0.93 ± 0.31 | 0.09 ± 0.17 |
| Spike waveform | |||
| Firing threshold (mV) | −52.4 ± 4.6 | −52.9 ± 4.9 | −54.5 ± 5.1 |
| Amplitude (mV) | 49.9 ± 9.4 | 63.1 ± 7.4 | 62.0 ± 5.9 |
| Half-width (ms) | 0.4 ± 0.1 | 0.8 ± 0.1 | 1.1 ± 0.3 |
| AHP amplitude (mV) | 10.6 ± 2.5 | 9.2 ± 2.9 | 8.1 ± 2.7 |
| Membrane potential distribution | |||
| Modal depolarised potential (mV) | −61.1 ± 3.5 | −68.4 ± 6.1 | −60.6 ± 4.0 |
| Modal hyperpolarised potential (mV) | −78.2 ± 6.2 | −86.2 ± 5.7 | — |
| Difference (mV) | 17.1 ± 5.1 | 17.8 ± 4.3 | — |
| Spontaneous spiking properties | |||
| Spike rate (Hz) | 6.3 ± 6.7 | 1.4 ± 1.7 | 3.6 ± 2.6 |
| Mean CV2 | 0.96 ± 0.23 | 1.25 ± 0.31 | 0.63 ± 0.25 |