NeuroElectro Publications

Article: Alpha-synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Wu N; Joshi PR; Cepeda C; Masliah E; Levine MS
J. Neurosci. Res., 2010

Table I. Passive Membrane Properties of MSSNs in WT and α-Syn mice

	35 day		90 day		300 day
	WT	α-Syn	WT	α-Syn	WT	α-Syn
* P < 0.05
Cm (pF)	95 ± 3	92 ± 4	95 ± 3	90 ± 3	96 ± 4	102 ± 3
Rm (MΩ)	137 ± 11	137 ± 14	105 ± 8	129 ± 12*	105 ± 8	117 ± 9
Tau (ms)	1.6 ± 0.1	1.6 ± 0.1	1.6 ± 0.1	1.7 ± 0.1	1.6 ± 0.1	1.9 ± 0.1

Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Neostriatum medium spiny neuron		input resistance (MΩ)	137.0 ± 11.0 (14)	137.0 (MΩ)	Data Table
Neostriatum medium spiny neuron		input resistance (MΩ)	105.0 ± 8.0 (27)	105.0 (MΩ)	Data Table
Neostriatum medium spiny neuron		input resistance (MΩ)	105.0 ± 8.0 (8)	105.0 (MΩ)	Data Table
Neostriatum medium spiny neuron		membrane time constant (ms)	1.6 ± 0.1 (14)	1.6 (ms)	Data Table
Neostriatum medium spiny neuron		membrane time constant (ms)	1.6 ± 0.1 (27)	1.6 (ms)	Data Table
Neostriatum medium spiny neuron		membrane time constant (ms)	1.6 ± 0.1 (8)	1.6 (ms)	Data Table
Neostriatum medium spiny neuron		cell capacitance (pF)	95.0 ± 3.0 (14)	95.0 (pF)	Data Table
Neostriatum medium spiny neuron		cell capacitance (pF)	95.0 ± 3.0 (27)	95.0 (pF)	Data Table
Neostriatum medium spiny neuron		cell capacitance (pF)	96.0 ± 4.0 (8)	96.0 (pF)	Data Table