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Article: Enhanced actions of adenosine in medial entorhinal cortex layer II stellate neurons in temporal lobe epilepsy are mediated via A(1)-receptor activation.

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Hargus NJ; Jennings C; Perez-Reyes E; Bertram EH; Patel MK
Epilepsia, 2012


Table 1.   Membrane properties of mEC layer II stellate neurons
 RMP (mV)Ri (MΩ)Threshold (mV)Width (msec)Amplitude (mV)Upstroke velocity (mV/ms)n
  1. ap < 0.001; bp < 0.01.

Control−61.0 ± 0.360.9 ± 1.3−45.8 ± 0.51.10 ± 0.0697.4 ± 1.0223.1 ± 6.319
TLE−59.1 ± 0.3a73.3 ± 2.8a−49.3 ± 0.7a1.13 ± 0.0697.1 ± 1.1258.3 ± 10.7b17

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Medial entorhinal cortex layer II stellate cell resting membrane potential (mV) -61.0 ± 0.3 (19) -61.0 (mV) Data Table
Medial entorhinal cortex layer II stellate cell input resistance (MΩ) 60.9 ± 1.3 (19) 60.9 (MΩ) Data Table
Medial entorhinal cortex layer II stellate cell spike threshold (mV) -45.8 ± 0.5 (19) -45.8 (mV) Data Table
Medial entorhinal cortex layer II stellate cell spike half-width (msec) 1.1 ± 0.06 (19) 1.1 (ms) Data Table
Medial entorhinal cortex layer II stellate cell spike amplitude (mV) 97.4 ± 1.0 (19) 97.4 (mV) Data Table
Medial entorhinal cortex layer II stellate cell spike max rise slope (mV/ms) 223.1 ± 6.3 (19) 223.1 (mV/ms) Data Table