Article: Altered intrinsic properties of neuronal subtypes in malformed epileptogenic cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) George AL; Jacobs KM Brain Res., 2011
Table 2Intrinsic properties of layer V interneurons and pyramidal cells.
All data are expressed as means±SE (n cells). Student's t-test was used to compare control and PMG values within each group, ** indicates p<0.05.
Electrophysiological parameter | FS | LTS | Pyr |
Control | Control | Control | |
PMG | PMG | PMG | |
Resting membrane potential, mV | −62.7±6.3 (31) | −55.4±4.2 (31) | −56.2±5.3 (28) |
−63.0±7.3 (24) | −58.7±5.2 (19)** | −57.3±8.2 (22) | |
Input resistance, MΩ | 120±7 (32) | 191±16 (32) | 121±16 (29) |
123±7 (25) | 173±22 (21) | 140±18 (21) | |
Spike amplitude, mV | 81.8±1.1 (34) | 99.2±1.4 (33) | 103.6±0.8 (28) |
85.3±1.3 (30)** | 96.3±1.7 (23) | 102.4±1.0 (16) | |
Max rate of rise, V/s | 256±12 (34) | 244±13 (33) | 287±11 (28) |
253±13 (30) | 239±11 (23) | 272±13 (16) | |
Max rate of decay, V/s | 117±7 (34) | 85±4 (33) | 42±2 (28) |
115±9 (30) | 84±5 (23) | 39±2 (16) | |
dV/dt ratio | 2.3±0.1 (34) | 2.9±0.1 (33) | 6.9±0.2 (28) |
2.4±0.1 (30) | 2.9±0.1 (23) | 7.1±0.3 (16) | |
Primary F/I slope (Hz/nA) | 407±25 (34) | 471±33 (33) | 87±18 (28) |
400±23 (30) | 481±41 (23) | 97±20 (16) |