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Article: Spike-timing-dependent plasticity of neocortical excitatory synapses on inhibitory interneurons depends on target cell type.

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Lu JT; Li CY; Zhao JP; Poo MM; Zhang XH
J. Neurosci., 2007


Table 2.

Properties of layer 2/3 PC–interneuron synaptic connections

PC-FS (n) PC-LTS (n)
Mean EPSP amplitude (mV) 2.95 ± 0.22 (142) 0.72 ± 0.08 (95)
Failure rate (%) 5.3 ± 0.8 (142) 48.9 ± 3.0 (95)
Paired-pulse ratio (%)a 76.1 ± 2.9 (43) 119 ± 12 (28)
Reciprocal connections (%)b 59.9 (97/162) 21.3 (32/150)
  • n, Number of cell pairs examined.

  • aPaired-pulse ratio was determined as the ratio of the amplitude of the first and the second EPSP evoked by two consecutive spikes in the PC at an interval of 100 ms.

  • bReciprocal connections refer to cell pairs that were synaptically interconnected.


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