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Article: Functional role of the fast transient outward K+ current IA in pyramidal neurons in (rat) primary visual cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Yuan W; Burkhalter A; Nerbonne JM J. Neurosci., 2005
Outward Kv currents in EGFP- and Kv4.2DN plus EGFP-expressing cortical neurons a
| EGFP | Kv4.2DN plus EGFP | Kv2.1DN plus EGFP | ||
|---|---|---|---|---|
| Peak (pA/pF) | 132 ± 13 | 120 ± 23 | 90 ± 10* | 99 ± 10 |
| IA (pA/pF) | 50 ± 4 | 48 ± 4 | ||
| IA τdecay (ms) | 67 ± 9 | 59 ± 8 | ||
| ID (pA/pF) | 25 ± 3 | 46 ± 14 | 28 ± 4 | 18 ± 3 |
| ID τdecay (ms) | 553 ± 81 | 538 ± 69 | 516 ± 76 | 540 ± 53 |
| IK (pA/pF) | 36 ± 4 | 44 ± 4 | 38 ± 4 | 20 ± 3** |
| IK τdecay (ms) | 2994 ± 213 | 1762 ± 222 | 2529 ± 259 | 3026 ± 270 |
| Iss (pA/pF) | 23 ± 2 | 30 ± 9 | 25 ± 2 | 16 ± 3 |
| n | 21 | 5 | 25 | 15 |
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*Peak current densities are significantly (p < 0.01) lower in Kv4.2DN plus EGFP-expressing cells than in cells expressing EGFP alone. **The value is significantly (p < 0.01) lower in Kv2.1DN plus EGFP-expressing cells than in EGFP- or Kv4.2DN plus EGFP-expressing cells.
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↵ a All values are means ± SEM; current densities were determined at +60 mV (holding potential, −70 mV); n = number of cells.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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