Property | Type I (n = 13) 23% | Type II (n = 35) 61% | Type III (n = 9) 16% | Pyramidal Cells (n = 13) |
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Rin, MΩ* P < 0.001 | 280 ± 513,PN | 230 ± 173,PN | 521 ± 911,2,PN | 59 ± 3.41,2,3 |
Tau, ms P = 0.077 | 18.8 ± 2.43 | 22.6 ± 1.5 | 29.3 ± 5.91,PN | 17 ± 1.43 |
RMP, mV* P < 0.001 | −68 ± 0.92,3,PN | −61 ± 0.91 | −58 ± 0.71 | −61 ± 0.81 |
ISI1, ms* P < 0.001 | 39.8 ± 5.6PN | 32.4 ± 4.43,PN | 62.9 ± 15.212,PN | 13.4 ± 5.41,2,3 |
ISIlast, ms P = 0.62 | 77 ± 11.12,3 | 113 ± 9.31 | 138 ± 25.91 | 110.5 ± 30.7 |
Spike adaptation ratio* P < 0.001 | 0.56 ± 0.062,PN | 0.29 ± 0.031,PN | 0.45 ± 0.08PN | 0.19 ± 0.081,2,3 |
Sag ratio* P < 0.001 | 0.006 ± 0.0012,3,PN | 0.04 ± 0.0061,3,PN | 0.064 ± 0.011,2 | 0.062 ± 0.0061,2 |
Rectification ratio* P = 0.011 | 1.68 ± 0.23 | 1.55 ± 0.063,PN | 1.11 ± 0.071,2 | 1.27 ± 0.072 |
Medium AHP, mV* P = 0.002 | 1.4 ± 0.42,3,PN | 2.2 ± 0.21 | 3.5 ± 0.81 | 3.4 ± 0.51 |
Fast AHP, mV* P = 0.016 | 12.4 ± 1.8 | 9.1 ± 1.03 | 16.1 ± 1.72,PN | 6.9 ± 0.93 |
Threshold, mV* P = 0.012 | −44 ± 1.13 | −45 ± 0.73 | −39 ± 1.51,2,PN | −43 ± 1.03 |
AP amplitude, mV* P < 0.001 | 75 ± 4.82,3,PN | 85 ± 2.81,3 | 58 ± 4.61,2,PN | 92.1 ± 2.91,3 |
AP half-width, ms* P < 0.001 | 1.03 ± 0.092PN | 1.06 ± 0.055PN | 1.01 ± 0.095PN | 0.74 ± 0.0521,2,3 |
Rise time, ms P = 0.052 | 0.45 ± 0.044 | 0.46 ± 0.027PN | 0.47 ± 0.036PN | 0.33 ± 0.032,3 |
Decay time, ms* P = 0.036 | 0.89 ± 0.11 | 1.13 ± 0.18PN | 0.75 ± 0.06 | 0.62 ± 0.072 |
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Values are means ± SE. Electrophysiological properties in bold are those used for clustering interneurons into subtypes. Asterisks (
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↵* ) indicate a significant difference among cell types based on an ANOVA, P < 0.05 (P values indicated). Superscript following the SE indicates cell type differences based on Fisher's post hoc analysis, P < 0.05. 1, Type I; 2, Type II; 3, Type III; PN, pyramidal neuron.