Article: Activation of alpha1-adrenoceptors increases firing frequency through protein kinase C in pyramidal neurons of rat visual cortex.
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Kobayashi M; Sasabe T; Shiohama Y; Koshikawa N
Neurosci. Lett., 2008
Table 2The effects of phenylephrine, isoproterenol, phorbol ester and chelerythrine on repetitive firing properties
| Slope | x-intercept |
| Early phasea (spikes/nA) | Late phase (spikes/nA)b | Early phase (nA)a |
| Control | 40.7±4.9 | 12.1±6.3 | 0.2±0.1 |
| Phenylephrine | 53.6±4.5* | 29.1±5.4** | 0.1±0.1* |
| n | 16 | 14 | 16 |
| Control | 29.1±4.4 | 9.1±4.5 | 0.3±0.1 |
| Isoproterenol | 45.6±3.8** | 33.0±4.3*** | 0.1±0.1* |
| n | 14 | 14 | 14 |
|
| Control | 41.1±7.5 | 20.6±8.9 | 0.2±0.1 |
| Phorbol ester | 61.1±6.1* | 26.3±8.6 | 0.0±0.0** |
| n | 8 | 8 | 8 |
|
| Chelerythrine | 51.3±6.4 | 31.8±11.5 | 0.2±0.1 |
| +Phenylephrine | 55.1±9.3 | 32.1±8.9 | 0.0±0.0 |
| n | 7 | 4 | 7 |
aEarly phase: 0ms≤t≤300ms.bLate phase: 300ms<t≤600ms.*P<0.05 (paired t-test).**P<0.01 (paired t-test).***P<0.001 (paired t-test).
Inferred neuron-electrophysiology data values
| Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
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