Table 1Membrane properties of gamma MNs (5-ht1d::GFP+, n=8), fast alpha MNs (n=7) and slow alpha MNs (n=8).
Property
Gamma
Fast-like
Slow-like
P value
Input resistance (MΩ)
82.60±12.66
56.75±5.36
132.83±13.59
<0.001*
Initial doublet (ms)
24.31±5.13
43.38±7.17
28.96±6.08
<0.05a
Firing frequency (Hz)
22.50±1.58
22.02±2.22
25.27±2.73
NS
AP threshold (mV)
−37.03±2.02
−33.33±3.99
−34.88±2.35
NS
AP half-width (ms)
0.72±0.04
0.57±0.02
0.82±0.05
<0.01a, <0.001b
AP delay (ms)
19.87±1.33
15.43±2.21
22.43±1.49
<0.05a, <0.01b
Rheobase current (pA)
235.00±30
361.43±45.33
175.00±30.65
<0.01*
AHP amplitude (mV)
3.49±0.63
3.93±0.49
4.16±0.68
NS
AHP time to peak (ms)
19.97±1.77
17.24±1.32
30.24±3.32
<0.05a, <0.01b
AHP half-decay time (ms)
43.01±3.38
32.90±3.22
60.61±5.17
<0.001*
* Indicates significant difference between all (one-way ANOVA); a indicates significant difference between Gamma and Fast (Student'st-test); b indicates significant difference between Fast and Slow (Student'st-test); NS, not significant. Values show±standard error of the mean (S.E.M).
