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Article: Differential modulatory effects of norepinephrine on synaptically driven responses of layer V barrel field cortical neurons.

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Waterhouse BD; Mouradian R; Sessler FM; Lin RC
Brain Res., 2000


Table 2Effects of adrenergic agonists on the probability of synaptically evoked spiking in different classes of layer V cortical neurons
Probability ofCell type
evoked spikingaRegularMixedIntrinsic
spikingburst/spikeburst
Norepinephrine (NE)Increased671
n=21No change000
Decreased034
Phenylephrine (PE)Increased23
n=8No change00
Decreased03b
Combined resultsIncreased8101
NE+PE(100%)(63%)(20%)
n=29No change000
(0%)(0%)(0%)
Decreased064
(0%)(37%)(80%)
aIncreased >20%, no change ≤20%, decreased >20%. bPE concentration ≥100 μM.

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