|
Article: Effects of resibufogenin on voltage-gated sodium channels in cultured rat hippocampal neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Hao S; Bao YM; Zhao RG; Wang HS; Bi J; An LJ; Jiang B Neurosci. Lett., 2011
Table 1Effects of RBG on properties of single action potential and number of action potentials in repetitive firing.
Values are mean±SEM.*P<0.05 vs. control.
| Control | RBG | n | |
| Number of APs | 7.50±1.17 | 5.83±0.51* | 8 |
| Peak amplitudes (mV) | 94.86±2.51 | 100.21±4.82* | 8 |
| Overshoot (mV) | 24.86±2.51 | 30.21±4.82* | 8 |
| Spike half-width (ms) | 3.32±0.25 | 2.01±0.17* | 8 |
| Peak rise time (10–90%) (ms) | 2.67±0.44 | 1.23±0.38* | 8 |
| Peak decay time (10–90%) (ms) | 4.67±0.59 | 4.27±0.63 | 8 |
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Hippocampus CA1 pyramidal cell | spike amplitude (mV) | 94.86 ± 2.51 (8) | 94.86 (mV) | Data Table | |
| Hippocampus CA1 pyramidal cell | spike peak (mV) | 24.86 ± 2.51 (8) | 24.86 (mV) | Data Table | |
| Hippocampus CA1 pyramidal cell | spike half-width (ms) | 3.32 ± 0.25 (8) | 3.32 (ms) | Data Table | |
| Hippocampus CA1 pyramidal cell | spike rise time | 2.67 ± 0.44 (8) | 2.67 (ms) | Data Table | |
| Hippocampus CA1 pyramidal cell | spike decay time | 4.67 ± 0.59 (8) | 4.67 (ms) | Data Table |