AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Differential regulation of synaptic transmission by adrenergic agonists via protein kinase A and protein kinase C in layer V pyramidal neurons of rat cerebral cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Kobayashi M
Neuroscience, 2007


Table 3Effects of second messengers downstream of α1- and β-adrenoceptors
TreatmentEPSPIPSP
Amplitude (mV)10–90% Rise time (ms)90–10% Decay time (ms)Half-duration (ms)Amplitude (mV)
Phorbol ester
Control6.1±0.97.9±2.267.2±12.529.2±04.70.4±0.2
Phorbol ester4.4±0.7⁎⁎7.6±1.651.9±11.730.7±5.90.5±0.2
n1312101313
Chelerythrine
Chelerythrine6.6±0.83.0±0.730.4±8.812.4±3.50.7±0.3
Chelerythrine+phenylephrine6.7±1.12.4±0.415.4±6.45.6±1.21.6±0.6
n97999
db-cAMP
Control3.8±0.69.4±2.165.5±17.524.0±4.20.7±0.4
db-cAMP5.1±0.8⁎⁎10.0±2.280.4±17.528.3±4.70.5±0.4
n1919191919
Ro 20–1724
Control3.0±0.46.9±1.378.3±19.925.6±4.80.2±0.1
Ro 20–1724a4.0±0.6⁎7.0±1.076.7±11.122.1±2.40.2±0.1
Ro 20–1724a3.4±0.46.7±1.267.6±9.023.0±3.30.2±0.1
Ro 20–1724+isoproterenol6.3±0.8⁎⁎⁎6.9±1.497.7±8.5⁎⁎⁎29.8±2.8⁎⁎⁎0.2±0.1
n1110101011
H-89
Control5.2±0.56.0±0.785.0±21.721.4±2.90.6±0.3
H-895.0±0.86.8±1.076.4±26.921.4±3.60.6±0.3
H-89+isoproterenol4.9±1.34.5±1.437.8±19.515.1±2.91.3±0.4
n74657
aBefore application of isoproterenol in combination with Ro 20–1724, intensity of electrical stimulation was reduced to avoid eliciting action potentials by isoproterenol-induced enhancement of eEPSPs.⁎P<0.05.⁎⁎P<0.01.⁎⁎⁎P<0.001 (paired t-test).

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source