Article: Activity-dependent serotonergic excitation of callosal projection neurons in the mouse prefrontal cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Stephens EK; Avesar D; Gulledge AT Front Neural Circuits, 2014
Comparison of 5-HT responses in CPn neurons with and without 2A receptors.
CPn neuron subtype | RMP (mV) | RN (MΩ) | Sag (%) | Duration of inhibition (s) |
||
---|---|---|---|---|---|---|
During low frequency firing | During high frequency firing | |||||
No revealed 2A-excitation | 21 | -76 ± 1 | 82 ± 6 | 12 ± 1 | 31 ± 3 | 20 ± 2 |
Revealed 2A-excitation | 10 | -76 ± 1 | 83 ± 11 | 14 ± 1 | 21 ± 3* | 17 ± 4 |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5 corticopontine pyramidal excitatory neurons without 2A receptors | sag ratio | 12.0 ± 1.0 (21) | 0.12 (ratio) | Data Table |
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5 corticopontine pyramidal excitatory neurons with 2A receptors | resting membrane potential (mV) | -76.0 ± 1.0 (10) | -76.0 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5 corticopontine pyramidal excitatory neurons with 2A receptors | input resistance (MΩ) | 83.0 ± 11.0 (10) | 83.0 (MΩ) | Data Table |
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5 corticopontine pyramidal excitatory neurons with 2A receptors | sag ratio | 14.0 ± 1.0 (10) | 0.14 (ratio) | Data Table |
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5 corticopontine pyramidal excitatory neurons without 2A receptors | resting membrane potential (mV) | -76.0 ± 1.0 (21) | -76.0 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5 corticopontine pyramidal excitatory neurons without 2A receptors | input resistance (MΩ) | 82.0 ± 6.0 (21) | 82.0 (MΩ) | Data Table |