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Article: Recording temperature affects the excitability of mouse superficial dorsal horn neurons, in vitro.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Graham BA; Brichta AM; Callister RJ
J. Neurophysiol., 2008



TABLE 1."Between-cell" and "within-cell" temperature effects on membrane and AP properties


Property Temperature

"Between-Cell" "Within-Cell"

Input resistance, MΩ
    RT 510 ± 26 (106)* 377 ± 28 (23)*
    PT 370 ± 14 (105) 278 ± 19 (23)
    Q10 0.73 0.74
RMP, mV
    RT –69.4 ± 0.7 (113)*
    PT –67.0 ± 0.8 (106)
    Q10 0.96
AP threshold, mV
    RT –40.3 ± 0.6 (110)* –42.4 ± 1.3 (23)
    PT –38.4 ± 0.5 (92) –41.8 ± 1.7 (23)
    Q10 0.94 0.98
AP amplitude, mV
    RT 60.7 ± 1.6 (111)* 78.8 ± 4.3 (23)*
    PT 50.3 ± 1.2 (93) 56.2 ± 3.9 (23)
    Q10 0.83 0.71
AP base width, ms
    RT 3.20 ± 0.08 (111)** 2.84 ± 0.20 (23)**
    PT 1.81 ± 0.04 (93) 1.64 ± 0.10 (23)
    Q10 0.57 0.58
AHP amplitude, mV
    RT –29.6 ± 1.7 (111) –31.3 ± 1.4 (23)
    PT –31.1 ± 0.9 (93) –35.2 ± 1.7 (23)
    Q10 1.05 1.12

Values are means ± SE, with number of neurons in parentheses. Values for "within-cell" temperature at RT and PT are calculated as the mean for heating and cooling experiments. Significant difference between RT and PT indicated (

* P < 0.05,

** P < 0.001, unpaired Student's t-test).


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