Article: A critical period for nicotine-induced disruption of synaptic development in rat auditory cortex.
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Aramakis VB; Hsieh CY; Leslie FM; Metherate R
J. Neurosci., 2000
Table 1.
EPSPs in layers II–IV pyramidal neurons of rat auditory cortex during normal development and after CNE
1-a
Age/condition |
Stimulus intensity (μA) |
Latency to peak (msec) |
Peak (mV) |
EPSP width @ one-third peak |
EPSP width @ one-half peak |
EPSP width @ two-thirds peak |
n |
Development |
P8–12 |
26.5 ± 7.0 |
16.8 ± 4.7 |
12.1 ± 1.3 |
107.8 ± 12.3 |
73.0 ± 8.5 |
50.6 ± 6.6 |
12 |
P13–16 |
22.7 ± 3.6 |
9.2 ± 0.7 |
15.3 ± 1.2 |
66.5 ± 7.7 |
48.3 ± 6.9 |
28.4 ± 1.9 |
17 |
P20–22 |
15.5 ± 5.0 |
5.7 ± 0.4 |
17.7 ± 1.0 |
34.5 ± 1.8 |
24.5 ± 1.4 |
16.4 ± 1.1 |
13 |
P24–26 |
12.4 ± 3.5 |
4.9 ± 0.5 |
23.0 ± 2.5 |
27.1 ± 2.4 |
18.3 ± 2.2 |
12.8 ± 1.6 |
5 |
Control |
38.8 ± 12.4 |
20.9 ± 8.7 |
11.0 ± 1.7 |
102.9 ± 16.7 |
72.7 ± 14.6 |
52.4 ± 12.1 |
6 |
CNE group I |
50.0 ± 15.8 |
20.0 ± 5.5 |
7.9 ± 2.2 |
115.5 ± 14.7 |
80.6 ± 10.2 |
53.6 ± 6.7 |
5 |
Control |
20.7 ± 2.9 |
10.2 ± 1.2 |
14.9 ± 1.1 |
76.3 ± 8.6 |
53.4 ± 6.2 |
32.8 ± 2.9 |
22 |
CNE group II |
1 mg/kg |
19.0 ± 2.6 |
14.5 ± 2.9 |
13.5 ± 1.3 |
112.3 ± 11.81-b
|
82.9 ± 10.41-b
|
61.9 ± 8.91-b
|
13 |
2 mg/kg |
17.5 ± 1.4 |
17.5 ± 4.1 |
12.9 ± 1.2 |
118.5 ± 14.91-b
|
82.4 ± 11.71-b
|
60.8 ± 10.01-b
|
9 |
Control |
10.1 ± 2.5 |
4.7 ± 0.3 |
21.2 ± 2.0 |
27.3 ± 1.9 |
18.5 ± 1.5 |
12.7 ± 1.1 |
8 |
CNE group III |
9.5 ± 1.8 |
14.8 ± 4.6 |
16.3 ± 2.0 |
46.6 ± 5.91-b
|
36.6 ± 5.51-b
|
28.8 ± 5.11-b
|
7 |
Control |
10.1 ± 2.5 |
4.7 ± 0.3 |
21.2 ± 2.0 |
27.3 ± 1.9 |
18.5 ± 1.5 |
12.7 ± 1.1 |
8 |
CNE group IV |
12.1 ± 2.6 |
5.6 ± 1.2 |
20.3 ± 1.6 |
33.7 ± 2.2 |
24.3 ± 2.4 |
17.1 ± 2.5 |
9 |
Inferred neuron-electrophysiology data values
Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
Content Source |