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Article: Cell type-specific effects of adenosine on cortical neurons.

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van Aerde KI; Qi G; Feldmeyer D
Cereb. Cortex, 2015


Table 5

Adenosine does not modulate passive properties of mPFC interneurons

Control 100 μM Adenosine Wash P
FS interneurons in mPFC (n = 14)
 RMP (mV) -72.7 ± 0.9 -72.6 ± 0.9 72.3 ± 1.0 0.43
 Input resistance (MΩ) 171 ± 12 175 ± 11 182 ± 14 0.57
 Time constant (ms) 8.6 ± 0.8 9.1 ± 0.7 10.0 ± 0.5 0.52
 Rheobase (pA) 184 ± 17 196 ± 17 179 ± 17 0.41
LTS interneurons in mPFC (n = 5)
 RMP (mV) -67.8 ± 1.2 -67.7 ± 1.2 - 0.71
 Input resistance (MΩ) 391 ± 64 438 ± 70 369 ± 43 0.17
 Time constant (ms) 30.2 ± 5.6 41.0 ± 6.6 31.2 ± 9.3 0.17
 Rheobase (pA) 20 ± 6 43 ± 10 53 ± 14 0.06/0.25
  • Note: Average ± SEM; RMP, resting membrane potential. P lists the results from paired t-tests between control and adenosine. When P < 0.10 the result from the paired t-test between adenosine and wash-out is also given.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source