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Article: Age-related changes to layer 3 pyramidal cells in the rhesus monkey visual cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Luebke JI; Medalla M; Amatrudo JM; Weaver CM; Crimins JL; Hunt B; Hof PR; Peters A
Cereb. Cortex, 2015


Table 4

Electrophysiologic properties

Young Aged P-value
Passive properties
 Tau (ms) 28.4 ± 2.9 25.7 ± 3.0 0.52
 Rn (MΩ) 285 ± 25.5 291 ± 27 0.87
 Vr (mV) -65.8 ± 0.83 -64.3 ± 1.0 0.22
AP properties
 Threshold (mV) -41.8 ± 0.74 -41.1 ± 0.7 0.52
 Amp. (mV) 71.0 ± 1.6 73.2 ± 1.9 0.38
 Dur. at 1/2 (ms) 1.44 ± 0.05 1.57 ± 0.06 0.11
 Rise (ms) 0.91 ± 0.03 0.98 ± 0.04 0.15
 Fall (ms) 2.12 ± 0.07 2.27 ± 0.10 0.21
Rheobase
 Amp. (pA) 87.2 ± 11.5 89.8 ± 13.2 0.88
Medium AHP
 Amp. (mV) -10.8 ± 0.66 -9.93 ± 0.37 0.31
 Dur. (ms) 67.0 ± 14.3 52.6 ± 6.5 0.40
Slow AHP
 Amp. (mV) -2.23 ± 0.49 -1.71 ± 0.28 0.37
 Dur. (ms) 691 ± 23 659 ± 42 0.47
AP firing rates (Hz)
 80-pA step 12.9 ± 1.2 11.5 ± 1.4 0.44
 100-pA step 13.2 ± 1.1 14.0 ± 1.4 0.65
 120-pA step 12.4 ± 1.4 14.9 ± 1.6 0.27
IH Amp. (pA)
 -140 mV step 221 ± 33 216 ± 43 0.91
IsAHP Amp. (pA)
 20-mV step 65.6 ± 8.5 85.4 ± 17.3 0.27
EPSCs
 Frequency 1.51 ± 0.34 1.27 ± 0.17 0.48
 Amplitude 6.43 ± 0.2 6.80 ± 0.3 0.34
 Area 42.9 ± 3.0 50.9 ± 3.7 0.10
 Rise 1.00 ± 0.06 1.26 ± 0.1 0.05
 Half-width 4.38 ± 0.21 5.57 ± 0.44 0.03
 Decay 4.22 ± 0.28 5.49 ± 0.5 0.05
IPSCs
 Frequency 0.33 ± 0.08 0.20 ± 0.06 0.11
 Amplitude 20.2 ± 1.1 19.6 ± 1.0 0.71
 Area 308 ± 24 299 ± 25 0.81
 Rise 2.78 ± 0.31 3.16 ± 0.30 0.39
 Half-width 9.46 ± 0.53 10.5 ± 1.1 0.36
 Decay 7.62 ± 0.60 7.63 ± 0.76 0.99

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons membrane time constant (ms) 28.4 ± 2.9 (30) 28.4 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons membrane time constant (ms) 25.7 ± 3.0 (26) 25.7 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons input resistance (MΩ) 285.0 ± 25.5 (30) 285.0 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons input resistance (MΩ) 291.0 ± 27.0 (26) 291.0 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons resting membrane potential (mV) -65.8 ± 0.83 (30) -65.8 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons resting membrane potential (mV) -64.3 ± 1.0 (26) -64.3 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons spike threshold (mV) -41.8 ± 0.74 (30) -41.8 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons spike threshold (mV) -41.1 ± 0.7 (26) -41.1 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons spike amplitude (mV) 71.0 ± 1.6 (30) 71.0 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons spike amplitude (mV) 73.2 ± 1.9 (26) 73.2 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons spike half-width (ms) 1.44 ± 0.05 (30) 1.44 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons spike half-width (ms) 1.57 ± 0.06 (26) 1.57 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons spike rise time (ms) 0.91 ± 0.03 (30) 0.91 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons spike rise time (ms) 0.98 ± 0.04 (26) 0.98 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons spike decay time (ms) 2.12 ± 0.07 (30) 2.12 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons spike decay time (ms) 2.27 ± 0.1 (26) 2.27 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons rheobase (pA) 87.2 ± 11.5 (30) 87.2 (pA) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons rheobase (pA) 89.8 ± 13.2 (26) 89.8 (pA) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons medium AHP amplitude (mV) -10.8 ± 0.66 (30) 10.8 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons medium AHP amplitude (mV) -9.93 ± 0.37 (26) 9.93 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons medium AHP duration (ms) 67.0 ± 14.3 (30) 67.0 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons medium AHP duration (ms) 52.6 ± 6.5 (26) 52.6 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons slow AHP amplitude (mV) -2.23 ± 0.49 (30) 2.23 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons slow AHP amplitude (mV) -1.71 ± 0.28 (26) 1.71 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons slow AHP duration (ms) 691.0 ± 23.0 (30) 691.0 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons slow AHP duration (ms) 659.0 ± 42.0 (26) 659.0 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons firing frequency 12.9 ± 1.2 (30) 12.9 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons firing frequency 11.5 ± 1.4 (26) 11.5 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons firing frequency 13.2 ± 1.1 (30) 13.2 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons firing frequency 14.0 ± 1.4 (26) 14.0 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal young neurons firing frequency 12.4 ± 1.4 (30) 12.4 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 Primary visual cortex layer 3 pyramidal aged neurons firing frequency 14.9 ± 1.6 (26) 14.9 (Hz) Data Table