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Article: Differences in intrinsic properties and local network connectivity of identified layer 5 and layer 6 adult mouse auditory corticothalamic neurons support a dual corticothalamic projection hypothesis.

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Llano DA; Sherman SM
Cereb. Cortex, 2009


Table 2

Summary of comparisons between juvenile and adult layer 5 corticothalamic neurons

Juvenile layer 5 corticothalamic (n = 35) Adult layer 5 corticothalamic (n = 47) P value
Ratio of cells with bursting 0/32 34/47 <0.001
Input resistance (MΩ) 176 ± 87 125 ± 41 0.006
Resting potential (mV) 63.3 ± 7.3 60.6 ± 6.1 0.115
τmembrane (ms) 28.4 ± 12.8 17.0 ± 16.5 0.001
Ih (pA) 44.8 ± 22.7 41.7 ± 22.2 0.554
DAP (mV) 0.84 ± 1.1 2.1 ± 2.4 0.003
AHP (mV) 2.7 ± 2.9 4.0 ± 3.7 0.082

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 regular firing corticothalamic pyramidal neurons input resistance (MΩ) 176.0 ± 87.0 176.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 regular firing corticothalamic pyramidal neurons resting membrane potential (mV) 63.3 ± 7.3 -63.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 regular firing corticothalamic pyramidal neurons membrane time constant (ms) 28.4 ± 12.8 28.4 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 regular firing corticothalamic pyramidal neurons ADP amplitude (mV) 0.84 ± 1.1 0.84 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 regular firing corticothalamic pyramidal neurons fast AHP amplitude (mV) 2.7 ± 2.9 2.7 (mV) Data Table