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Article: Transient Hearing Loss Within a Critical Period Causes Persistent Changes to Cellular Properties in Adult Auditory Cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Mowery TM; Kotak VC; Sanes DH
Cereb. Cortex, 2015


Table 1

CPs for membrane properties

n RMP (mV) AP Amp (mV) AP Thresh (mV) Rin (MΩ) τ (ms) AP width (ms) Sag (mV) ΔmV (mV/10 pA)
Ctrl (P23) 24 -64.5 ± 0.6 97.5 ± 2.2 -31.8 ± 1.2 141 ± 12 11.5 ± 1.2 1.2 ± 0.1 1.4 ± 0.1 1.7 ± 0.1
EP11-23 31 -58.7 ± 0.5*** 88.4 ± 1.9* -26.5 ± 1.1* 179 ± 10 19.1 ± 1.0 1.4 ± 0.0* 2.1 ± 0.1** 2.5 ± 0.3
EP12-23 16 -59.1 ± 0.7*** 88.2 ± 2.7* -26.1 ± 1.5 198 ± 14* 24.0 ± 1.5** 1.7 ± 0.1** 2.4 ± 0.0*** 3.0 ± 0.2**
EP13-23 19 -61.1 ± 0.7* 85.2 ± 2.4** -28.7 ± 1.4 218 ± 13** 19.2 ± 1.3 1.5 ± 0.1* 2.5 ± 0.1*** 2.9 ± 0.5**
EP14-23 28 -63.5 ± 0.5 95.1 ± 2.4 -32.4 ± 1.3 125 ± 11 8.3 ± 1.1 1.2 ± 0.1 0.8 ± 0.1 1.3 ± 0.1
EP15-23 27 -64.6 ± 0.6 96.4 ± 2.8 -31.1 ± 1.3 144 ± 11 11.1 ± 0.6 1.3 ± 0.1 0.7 ± 0.0** 1.4 ± 0.1
EP16-23 10 -65.0 ± 0.8 96.7 ± 2.0 -31.4 ± 0.9 116 ± 14 10.8 ± 1.8 1.0 ± 0.1 0.8 ± 0.9* 1.3 ± 0.1
EP17-23 11 -66.2 ± 0.8 95.1 ± 1.7 -31.8 ± 0.6 106 ± 11 14.0 ± 1.4 1.1 ± 0.1 0.6 ± 0.6* 1.2 ± 0.1
Ctrl (P35) 24 -64.2 ± 0.5 99.1 ± 1.3 -32.5 ± 1.0 118 ± 9 8.4 ± 0.8 1.0 ± 0.0 1.3 ± 0.1 1.5 ± 0.0
EP18-35 25 -66.4 ± 0.8 98.7 ± 2.0 -32.5 ± 2.4 87 ± 6 11.1 ± 0.6 1.0 ± 0.1 1.3 ± 0.2 1.6 ± 0.2
EP19-35 27 -66.7 ± 0.7 106.3 ± 1.4 -34.9 ± 1.2 134 ± 11 10.8 ± 1.8 1.1 ± 0.0 1.3 ± 0.0 1.6 ± 0.2
EP23-35 44 -65.0 ± 0.4 100.7 ± 1.4 -33.4 ± 0.8 124 ± 7 8.5 ± 0.6 1.0 ± 0.0 1.3 ± 0.1 1.5 ± 0.0

  • RMP, resting membrane potential; AP amp, action potential amplitude; AP threshold, voltage threshold to spike; Rin, input resistance; τ, membrane time constant; AP width, action potential HW; Sag, depolarizing sag; ΔmV, change in membrane voltage per 10 pA step. EP, earplug insertion days.

  • *P < 0.05, **P < 0.01, ***P < 0.001.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell resting membrane potential (mV) -64.5 ± 0.6 (24) -64.5 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell spike amplitude from resting (mV) 97.5 ± 2.2 (24) 97.5 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell spike threshold (mV) -31.8 ± 1.2 (24) -31.8 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell input resistance (MΩ) 141.0 ± 12.0 (24) 141.0 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell membrane time constant (ms) 11.5 ± 1.2 (24) 11.5 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell spike half-width (ms) 1.2 ± 0.1 (24) 1.2 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell resting membrane potential (mV) -64.2 ± 0.5 (24) -64.2 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell spike amplitude from resting (mV) 99.1 ± 1.3 (24) 99.1 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell spike threshold (mV) -32.5 ± 1.0 (24) -32.5 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell input resistance (MΩ) 118.0 ± 9.0 (24) 118.0 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell membrane time constant (ms) 8.4 ± 0.8 (24) 8.4 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell spike half-width (ms) 1.0 (24) 1.0 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell sag amplitude (mV) 1.3 ± 0.1 (24) 1.3 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Auditory Cortex layer 2-3 pyramidal cell sag amplitude (mV) 1.4 ± 0.1 (24) 1.4 (mV) Data Table