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Article: Functional roles of Kv1 channels in neocortical pyramidal neurons.

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Guan D; Lee JC; Higgs MH; Spain WJ; Foehring RC
J. Neurophysiol., 2007



TABLE 3.Action potential waveform data


Vfirst Peak I, pA % at APW Peak Peak Time % DTX Peak % DTX-insens Peak

DTX-sensitive –39.2 ± 18.3 262 ± 167* 10.9 ± 5.2* 1.0 ± 0.3 36.5 ± 36.1 10.9 ± 3.3*
DTX-insensitive –37.8 ± 19.1 1,486 ± 815 90.5 ± 7.7 0.6 ± 0.4 64.5 ± 37.0 89.1 ± 3.3

Values are means ± SD; dissociated cells: n = 9 cells. Voltage protocol was as in Fig. 5E. Vfirst, voltage at which current first detected. Peak I, peak current for this component (pA). APW, action potential waveform (series of ramps from –70 to +30 mV and return to –70 mV (3.6-ms base width). % at APW Peak, percentage of the whole current arising from this component at a time corresponding to the peak of the AP waveform used as voltage stimulus. Peak Time, time (ms) after peak of APW (which occurred at 1.8 ms in protocol). % DTX Peak, percentage of whole current arising from this component at a time corresponding to peak DTX-sensitive current. % DTX-insens Peak, percentage of whole current arising from this component at a time corresponding to peak of the DTX-insensitive current. Significant difference:

* P < 0.05.


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