Article: Sympathetic sprouting near sensory neurons after nerve injury occurs preferentially on spontaneously active cells and is reduced by early nerve block.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Xie W; Strong JA; Li H; Zhang JM
J. Neurophysiol., 2007

TABLE 1.Effect of early nerve blockade on electrical parameters



	Normal	Axotomy	Axotomy + ACSF	Axotomy + TTX

Large-diameter cells (>50 µm)
n	87 cells, 5 animals	190 cells, 8 animals	170 cells, 7 animals	137 cells, 6 animals
V_m, mV	–60.06 ± 0.69	–56.7 ± 1.5^***	–56.7 ± 0.5^***	–56.6 ± 0.61^**
Rheobase, nA	1.18 ± 0.07	0.61 ± 0.02^***	0.71 ± 0.02^***	0.93 ± 0.05^*^§
AP threshold, mV	–38.5 ± 0.99	–40.5 ± 0.57^*	–40.7 ± 0.51^*	–36.3 ± 0.73^§
AP duration, ms	0.83 ± 0.04	1.53 ± 0.05^***	1.55 ± 0.05^***	1.60 ± 0.07^***
AP amplitude, mV	39.2 ± 1.22	44.2 ± 0.61^***	47 ± 0.58^***	46 ± 0.80^***
AHP duration, ms	2.3 ± 0.11	5.0 ± 0.27^***	4.5 ± 0.24^***	4.4 ± 0.31^***
AHP amplitude, mV	13.1 ± 0.34	7.7 ± 0.27^***	8.4 ± 0.26^***	7.4 ± 0.30^***
R_in, MΩ	24.8 ± 0.97	33.5 ± 0.80^***	27.7 ± .80^*	31.4 ± 1.00^**
Medium-diameter cells (30–50 µm)
n	58 cells, 5 animals	67 cells, 8 animals	81 cells, 7 animals	73 cell, 6 animals
V_m, mV	–57.6 ± 0.90	–54.3 ± 0.94^*	–53.4 ± 0.92^*	–53.8 ± 0.78^*
Rheobase, nA	1.00 ± 0.08	0.57 ± 0.05^***	0.65 ± 0.04^***	0.81 ± 0.05^*^§
AP threshold, mV	–34.4 ± 1.53	–35.9 ± 0.94	–36.6 ± 0.91	–31.8 ± 1.10^§
AP duration, ms	1.16 ± 0.07	1.90 ± 0.09^***	1.80 ± 0.09^***	2.0 ± 0.09^***
AP amplitude, mV	44.1 ± 1.6	50 ± 1.54	49 ± 1.21^*	49.4 ± 1.20^*
AHP duration, ms	2.61 ± 0.17	5.25 ± 0.42^***	4.65 ± 0.29^***	4.3 ± 0.33^***
AHP amplitude, mV	15.0 ± 0.70	10.2 ± 0.62^**	11.6 ± 0.56^**	9.8 ± 0.63^***
R_in, MΩ	41.7 ± 2.92	50.3 ± 2.3	41.5 ± 2.3	46.4 ± 3.10
Small-diameter cells (<30 µm)
n	42 cells, 5 animals	35 cells, 8 animals	54 cells, 7 animals	41 cells, 6 animals
V_m, mV	–58.1 ± 1.70	–51.2 ± 1.83^*	–52.4 ± 0.98^*	–52.02 ± 1.23^*
Rheobase, nA	1.06 ± 0.08	0.78 ± 0.06^**	0.73 ± 0.04^**	0.72 ± 0.04^**
AP threshold, mV	–17.62 ± 1.70	–23.1 ± 1.66^*	–24.5 ± 1.04^**	–25.6 ± 1.24^**
AP duration, ms	3.0 ± 0.34	2.9 ± 0.25	2.80 ± 0.14	2.47 ± 0.11
AP amplitude, mV	51.7 ± 1.18	48.3 ± 2.24	50.9 ± 1.12	50.0 ± 1.41
AHP duration, ms	6.0 ± 0.55	5.3 ± 0.52	4.4 ± 0.27^*	3.45 ± 0.22^*
AHP amplitude, mV	17.4 ± 0.93	16 ± 1.08	17.5 ± 0.50	17.06 ± 0.73
R_in, MΩ	91.9 ± 7.56	79.4 ± 5.30	90 ± 4.7	76.5 ± 4.30

Cell diameters were obtained from microscopic observations made during intracellular recording. Values are means ± SE. AP, action potential, AHP, afterhyperpolarization. R_in, input resistance; ACSF, artificial cerebrospinal fluid. Compared with normal value,

^*** , P < 0.0001;

^** , P < 0.001;

^* , P < 0.05 Compared with axotomy and axotomy + ACSF group.

^§ , P < 0.05

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type	Ephys Prop	Extracted Value	Standardized Value	Content Source
Dorsal root ganglion cell	AHP amplitude (mV)	15.0 ± 0.7	--	Data Table
Dorsal root ganglion cell	input resistance (MΩ)	41.7 ± 2.92	--	Data Table
Dorsal root ganglion cell	resting membrane potential (mV)	-58.1 ± 1.7	--	Data Table
Dorsal root ganglion cell	rheobase (nA)	1.06 ± 0.08	--	Data Table
Dorsal root ganglion cell	spike threshold (mV)	-17.62 ± 1.7	--	Data Table
Dorsal root ganglion cell	spike width (ms)	3.0 ± 0.34	--	Data Table
Dorsal root ganglion cell	spike amplitude (mV)	51.7 ± 1.18	--	Data Table
Dorsal root ganglion cell	AHP duration (ms)	6.0 ± 0.55	--	Data Table
Dorsal root ganglion cell	AHP amplitude (mV)	17.4 ± 0.93	--	Data Table
Dorsal root ganglion cell	input resistance (MΩ)	91.9 ± 7.56	--	Data Table
Dorsal root ganglion cell	resting membrane potential (mV)	-60.06 ± 0.69	--	Data Table
Dorsal root ganglion cell	rheobase (nA)	1.18 ± 0.07	--	Data Table
Dorsal root ganglion cell	spike threshold (mV)	-38.5 ± 0.99	--	Data Table
Dorsal root ganglion cell	spike width (ms)	0.83 ± 0.04	--	Data Table
Dorsal root ganglion cell	spike amplitude (mV)	39.2 ± 1.22	--	Data Table
Dorsal root ganglion cell	AHP duration (ms)	2.3 ± 0.11	--	Data Table
Dorsal root ganglion cell	AHP amplitude (mV)	13.1 ± 0.34	--	Data Table
Dorsal root ganglion cell	input resistance (MΩ)	24.8 ± 0.97	--	Data Table
Dorsal root ganglion cell	resting membrane potential (mV)	-57.6 ± 0.9	--	Data Table
Dorsal root ganglion cell	rheobase (nA)	1.0 ± 0.08	--	Data Table
Dorsal root ganglion cell	spike threshold (mV)	-34.4 ± 1.53	--	Data Table
Dorsal root ganglion cell	spike width (ms)	1.16 ± 0.07	--	Data Table
Dorsal root ganglion cell	spike amplitude (mV)	44.1 ± 1.6	--	Data Table
Dorsal root ganglion cell	AHP duration (ms)	2.61 ± 0.17	--	Data Table