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Article: Potentially epileptogenic dysfunction of cortical NMDA- and GABA-mediated neurotransmission in Otx1-/- mice.

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Sancini G; Franceschetti S; Lavazza T; Panzica F; Cipelletti B; Frassoni C; Spreafico R; Acampora D; Avanzini G
Eur. J. Neurosci., 2001


Table 2. Adapting regular spiking (RSAD) neurons. Early and late excitatory postsynaptic potentials (eEPSP and lEPSP) and fast and slow inhibitory postsynaptic potentials (fIPSP and sIPSP)
Otx1-/- (n = 22)Wild-type (n = 12)
Time to peak (ms)Amplitude (mV)Integral (mV·ms)Time to peak (ms)Amplitude (mV)Integral (mV ms)
eEPSP6.9 ± 0.97.8 ± 0.61252 ± 1676.7 ± 1.58.5 ± 1.3806 ± 171*
lEPSP-- --
fIPSP16.9 ± 0.85.8 ± 0.72572 ± 29919.2 ± 1.44.5 ± 0.6*1057 ± 282
sIPSP207.9 ± 8.67.9 ± 0.6 206.0 ± 7.93.8 ± 0.8

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source