TABLE 1.Intrinsic properties of pyramidal neurons
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Wild-type | Knockout | |
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Vm, mV | –66.3 ± 0.8 | –65.6 ± 0.9 |
Rin, MΩ | 286 ± 23 | 293 ± 22 |
τ, ms | 30 ± 2 | 33 ± 2 |
Ith, pA | 61 ± 6 | 57 ± 6 |
Vth, mV | –40.8 ± 0.7 | –41.3 ± 0.7 |
Sag, mV | 2.5 ± 0.3 | 2.7 ± 0.3 |
A summary of the basic intrinsic properties of layer V pyramidal neurons in somatosensory cortex of wild-type (n = 24) and
Fmr1 knockout (KO) (n = 31) mice. These include resting potential (Vm), resting input resistance (Rin), time constant (τ), threshold or rheobase current (Ith), threshold potential (Vth), and sag potential (mV, measured from the response to a –100-pA step). Mean values are shown ± SE. No differences are significant.