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Article: Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Kron M; Howell CJ; Adams IT; Ransbottom M; Christian D; Ogier M; Katz DM
J. Neurosci., 2012


Table 3.

Membrane properties of second-order nTS relay neurons (lnTS)

Juvenile lnTS Adult lnTS
Wt (n = 26) Null (n = 30) Wt (n = 21) Null (n = 18)
Vm (mV) -64.5 ± 2.1 -59.5 ± 1.4* -60.4 ± 1.8 -62.9 ± 2.6
Cm (pF) 37.8 ± 2.4 36.8 ± 2.7 34.6 ± 3.0 29.9 ± 1.9
Rm (mΩ) 440.6 ± 60.0 462.0 ± 75.0 447.3 ± 56.3 464.5 ± 51.5

  • Data are displayed as mean ± SEM;

  • ↵*p < 0.05.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Other lateral nucleus tractus solitarius second-order relay neurons resting membrane potential (mV) -64.5 ± 2.1 (26) -64.5 (mV) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons resting membrane potential (mV) -60.4 ± 1.8 (21) -60.4 (mV) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons cell capacitance (pF) 37.8 ± 2.4 (26) 37.8 (pF) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons cell capacitance (pF) 34.6 ± 3.0 (21) 34.6 (pF) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons input resistance (mΩ) 440.6 ± 60.0 (26) 440.6 (MΩ) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons input resistance (mΩ) 447.3 ± 56.3 (21) 447.3 (MΩ) Data Table