Article: Oxidative stress induced by cumene hydroperoxide evokes changes in neuronal excitability of rat motor cortex neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Pardillo-Díaz R; Carrascal L; Ayala A; Nunez-Abades P
Neuroscience, 2015

Membrane properties	Control	CH (5 min)	CH (15 min)	CH (30 min)
Membrane potential (mV) n = 30	-70.7 ± 1.3	-67.0 ± 1.2^∗+	-65.1 ± 1.7^∗	-64.2 ± 1.4^∗
Input resistance (MΩ) n = 30	188.4 ± 19.0	219.9 ± 24.3^∗+	134.3 ± 16.2^∗+	120.7 ± 16.7^∗
Rheobase (pA) n = 30	176.5 ± 22.4	151.0 ± 20.9^∗+	278.7 ± 40.2^∗+	287.9 ± 44.3^∗
Voltage depolarization (mV) n = 30	31.3 ± 1.2	28.2 ± 1.8^∗+	27.4 ± 1.8^∗	25.5 ± 2.2^∗
Voltage threshold (mV) n = 30	-39.4 ± 1.6	-38.8 ± 2.0	-38.9 ± 2.2	-38.7 ± 2.4
Action potential amplitude (mV) n = 30	118.0 ± 0.5	109.3 ± 1.1^∗+	106.0 ± 1.7^∗	99.2 ± 0.7^∗+
Action potential duration (ms) n = 30	1.44 ± 0.02	1.67 ± 0.04^∗+	1.72 ± 0.07^∗	2.05 ± 0.09^∗+
Gain (AP s^-1 nA^-1) n = 17	44.1 ± 5.9	37.4 ± 9.0	29.7 ± 8.6^∗	20.6 ± 7.8^∗
Maximum frequency (AP s^-1) n = 17	29.3 ± 3.5	19.2 ± 3.8^∗+	15.5 ± 3.5^∗	12.2 ± 3.1^∗
Cancelation current (pA) n = 17	782.7 ± 52.8	715.2 ± 65.1	614.6 ± 56.8^∗	545.2 ± 63.8^∗

Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Neocortex pyramidal cell layer 5-6	Primary motor cortex layer 5 pyramidal cell	rheobase (pA)	176.5 ± 22.4 (30)	176.5 (pA)	Data Table
Neocortex pyramidal cell layer 5-6	Primary motor cortex layer 5 pyramidal cell	resting membrane potential (mV)	-70.7 ± 1.3 (30)	-70.7 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	Primary motor cortex layer 5 pyramidal cell	spike threshold (mV)	-39.4 ± 1.6 (30)	-39.4 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	Primary motor cortex layer 5 pyramidal cell	spike amplitude from resting (mV)	118.0 ± 0.5 (30)	118.0 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	Primary motor cortex layer 5 pyramidal cell	spike half-width (ms)	1.44 ± 0.02 (30)	1.44 (ms)	Data Table
Neocortex pyramidal cell layer 5-6	Primary motor cortex layer 5 pyramidal cell	FI slope	44.1 ± 5.9 (30)	44.1 (Hz/nA)	Data Table
Neocortex pyramidal cell layer 5-6	Primary motor cortex layer 5 pyramidal cell	maximum firing rate	29.3 ± 3.5 (30)	29.3 (Hz)	Data Table
Neocortex pyramidal cell layer 5-6	Primary motor cortex layer 5 pyramidal cell	input resistance (MΩ)	188.4 ± 19.0 (30)	188.4 (MΩ)	Data Table