Article: Electrophysiological properties of genetically identified subtypes of layer 5 neocortical pyramidal neurons: Ca²⁺ dependence and differential modulation by norepinephrine.

Table 3.

Peak and slow AHPs

Data are presented as mean ± SE (n, number of cells). Afterhyperpolarizations (AHPs) were elicited in response to 10 suprathreshold, 5-ms current injections at 50 Hz. Note that the RMP when this protocol was run was significantly more negative in the layer 2/3 cells (-78 ± 1 mV) vs. the layer 5 cells (-74 ± 0.5 for etv1 and -74 ± 0.4 mV for glt), which likely contributed to the smaller AHP amplitudes in these cells.
↵* Significant difference, glt from etv1 (P < 0.05, unpaired t-test).
↵† Significant difference vs. layer 2/3 (ANOVA with Tukey's post hoc test). sAHP, slow AHP.

Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5a corticostriatal Etv1-expressing slender-tufted pyramidal neurons	medium AHP amplitude from resting (mV)	6.6 ± 0.3 (77)	6.6 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5a corticostriatal Etv1-expressing slender-tufted pyramidal neurons	slow AHP amplitude from resting (mV)	3.2 ± 0.2 (77)	3.2 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5b Glt25d2-expressing thick-tufted pyramidal neurons	medium AHP amplitude from resting (mV)	5.5 ± 0.2 (62)	5.5 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5b Glt25d2-expressing thick-tufted pyramidal neurons	slow AHP amplitude from resting (mV)	0.8 ± 0.2 (62)	0.8 (mV)	Data Table
Neocortex pyramidal cell layer 2-3	somatosensory cortex layer 2/3 pyramidal neurons	medium AHP amplitude from resting (mV)	3.7 ± 0.4 (21)	3.7 (mV)	Data Table
Neocortex pyramidal cell layer 2-3	somatosensory cortex layer 2/3 pyramidal neurons	slow AHP amplitude from resting (mV)	1.3 ± 0.2 (21)	1.3 (mV)	Data Table