Article: Intrinsic neurophysiological properties of hilar ectopic and normotopic dentate granule cells in human temporal lobe epilepsy and a rat model.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Althaus AL; Sagher O; Parent JM; Murphy GG J. Neurophysiol., 2015
GCL DGCs | Hilar DGCs | Interneurons | |
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n | 36 | 7 | 11 |
Resting membrane potential*, mV | -70.47 ± 0.82 | -68.81 ± 1.96 | -64.18 ± 1.23‡ |
Input resistance*, MΩ | 198.58 ± 15.43 | 153.32 ± 16.9 | 142.07 ± 57.04 |
Sag ratio* | 1.12 ± 0.01 | 1.07 ± 0.04 | 1.25 ± 0.08‡ |
Action potential threshold*, mV | -42.98 ± 1.45 | -22.87 ± 8.14‡ | -42.47 ± 2.51† |
Action potential spike height*, mV | 79.69 ± 2.21 | 53.72 ± 11.37‡ | 69.96 ± 4.01 |
Action potential half-width, ms | 0.99 ± 0.05 | 0.92 ± 0.13 | 0.77 ± 0.09 |
Values are means ± SE; n, no. of cells.
GCL, granule cell layer; DGC, dentate granule cells. Analyses were done using one-way ANOVA with Tukey's post hoc test for multiple comparisons. Action potential characteristics were measured from single-spike protocol.
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↵* Main effect determined by one-way ANOVA.
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↵‡ Significantly different from GCL with post hoc analysis.
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↵† Significantly different from hilus with post hoc analysis.
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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