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Article: Functional properties of GABA synaptic inputs onto GABA neurons in monkey prefrontal cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Rotaru DC; Olezene C; Miyamae T; Povysheva NV; Zaitsev AV; Lewis DA; Gonzalez-Burgos G J. Neurophysiol., 2015
Table 1.
Summary of electrophysiological intrinsic membrane properties of subclasses of interneurons in layer 3 of monkey DLPFC
| Cell Class | Time Constant, ms | Input Resistance, MΩ | Spike Duration, ms | Adaptation Ratio (last ISI/first ISI) | Spike Threshold, mV | AHP Amplitude, mV |
|---|---|---|---|---|---|---|
| FS (n = 34) | 9.21 ± 0.62a | 155 ± 16a | 0.45 ± 0.01a | 1.07 ± 0.02a | -50.5 ± 1.0a | 18.9 ± 1.1a |
| RS (n = 24) | 22.40 ± 1.48b | 318 ± 32b | 0.84 ± 0.05b | 2.03 ± 0.13b | -51.8 ± 1.9a | 12.0 ± 0.9b |
| BS (n = 6) | 22.51 ± 5.49b | 292 ± 26b | 1.09 ± 0.11c | 4.17 ± 0.87b | -55.6 ± 1.4a | 5.7 ± 1.5c |
| IS (n = 6) | 14.3 ± 1.6a,b | 288 ± 72b | 0.66 ± 0.11b | 3.23 ± 0.69b | -53.5 ± 1.6a | 12.9 ± 2.4b |
Except for spike threshold, all other electrophysiological properties showed significant differences between group means, as determined by single-factor ANOVA. In each column, groups labeled with a different letter are significantly different, as determined by Fisher least significant difference (LSD) comparisons (P < 0.05).
DLPFC, dorsolateral prefrontal cortex; FS, fast spiking; RS, regular spiking; BS, burst spiking; IS, irregular spiking; ISI, interspike interval; AHP, afterhyperpolarization.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal regular spiking neuron | input resistance (MΩ) | 318.0 ± 32.0 (24) | 318.0 (MΩ) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal regular spiking neuron | spike width (ms) | 0.84 ± 0.05 (24) | 0.84 (ms) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal regular spiking neuron | adaptation ratio (last/first ISI) | 2.03 ± 0.13 (24) | 2.03 (ratio) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal regular spiking neuron | spike threshold (mV) | -51.8 ± 1.9 (24) | -51.8 (mV) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal regular spiking neuron | AHP amplitude (mV) | 12.0 ± 0.9 (24) | 12.0 (mV) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal burst spiking neuron | membrane time constant (ms) | 22.51 ± 5.49 (6) | 22.51 (ms) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal burst spiking neuron | input resistance (MΩ) | 292.0 ± 26.0 (6) | 292.0 (MΩ) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal burst spiking neuron | spike width (ms) | 1.09 ± 0.11 (6) | 1.09 (ms) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal burst spiking neuron | adaptation ratio (last/first ISI) | 4.17 ± 0.87 (6) | 4.17 (ratio) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal fast spiking neuron | membrane time constant (ms) | 9.21 ± 0.62 (34) | 9.21 (ms) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal burst spiking neuron | spike threshold (mV) | -55.6 ± 1.4 (6) | -55.6 (mV) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal burst spiking neuron | AHP amplitude (mV) | 5.7 ± 1.5 (6) | 5.7 (mV) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal irregular spiking neuron | membrane time constant (ms) | 14.3 ± 1.6 (6) | 14.3 (ms) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal irregular spiking neuron | input resistance (MΩ) | 288.0 ± 72.0 (6) | 288.0 (MΩ) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal irregular spiking neuron | spike width (ms) | 0.66 ± 0.11 (6) | 0.66 (ms) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal irregular spiking neuron | adaptation ratio (last/first ISI) | 3.23 ± 0.69 (6) | 3.23 (ratio) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal irregular spiking neuron | spike threshold (mV) | -53.5 ± 1.6 (6) | -53.5 (mV) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal irregular spiking neuron | AHP amplitude (mV) | 12.9 ± 2.4 (6) | 12.9 (mV) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal fast spiking neuron | input resistance (MΩ) | 155.0 ± 16.0 (34) | 155.0 (MΩ) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal fast spiking neuron | spike width (ms) | 0.45 ± 0.01 (34) | 0.45 (ms) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal fast spiking neuron | adaptation ratio (last/first ISI) | 1.07 ± 0.02 (34) | 1.07 (ratio) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal fast spiking neuron | spike threshold (mV) | -50.5 ± 1.0 (34) | -50.5 (mV) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal fast spiking neuron | AHP amplitude (mV) | 18.9 ± 1.1 (34) | 18.9 (mV) | Data Table |
| Other | Dorsolateral prefrontal cortex layer 3 non-pyamidal regular spiking neuron | membrane time constant (ms) | 22.4 ± 1.48 (24) | 22.4 (ms) | Data Table |