Article: Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch.
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Dehorter N; Ciceri G; Bartolini G; Lim L; del Pino I; Marín O
Science, 2015
Figure S9: Fig. S9. Er81 cell autonomously controls intrinsic properties on PV+ interneurons.
|
Cre;Er81+/+ |
Cre;Er81F/F |
P values |
| Vrest (mV) |
-72.4 +/- 1.0 |
-68.9 +/- 1.9 |
0.12 |
| Cm (pF) |
38.4 +/- 1.6 |
35.0 +/- 1.8 |
0.17 |
| Rm (MOhm) |
124.3 +/- 10.6 |
161.8 +/- 13.4 |
(*) 0.03 |
| Rheobase (pA) |
246.7 +/- 23.8 |
180.5 +/- 17.3 |
(*) 0.04 |
| V threshold (mV) |
-34.3 +/- 0.7 |
-37.8 +/- 2.1 |
(*) 0.04 |
| AP amplitude (mV) |
52.3 +/- 2.2 |
52.2 +/- 2.9 |
0.97 |
| AP rise duration (ms) |
0.21 +/- 0.01 |
0.26 +/- 0.02 |
(*) 0.02 |
| AP tot duration (ms) |
0.76 +/- 0.03 |
0.89 +/- 0.06 |
(*) 0.04 |
| AHP amplitude (mV) |
20.22 +/- 0.79 |
18.15 +/- 0.86 |
0.09 |
| AHP duration (ms) |
0.15 +/- 0.01 |
0.17 +/- 0.02 |
0.18 |
| Latency to the 1st spike (ms) |
287.5 +/- 23.3 |
136.9 +/- 24.9 |
(***) 0.00009 |
| Exponential fit (mV) |
4.5 +/- 0.5 |
3.0 +/- 0.4 |
(*) 0.03 |
| MFF (Hz) |
129.3 +/- 13.2 |
134.9 +/- 14.8 |
0.9 |
| Number of cells |
21 |
17 |
|
| (D) Intrinsic electrophysiological properties of control and Er81 mutant PV+ interneurons in cortical layer II-III. Vrest: resting membrane potential; Cm: membrane capacitance; Rm: membrane resistance; Vthreshold: Threshold potential for spike; AP: Action potential; AHP: After hyperpolarization; MFF: Maximum firing frequency.: |
Inferred neuron-electrophysiology data values
| Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
Content Source |
