AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Threshold firing frequency-current relationships of neurons in rat somatosensory cortex: type 1 and type 2 dynamics.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Tateno T; Harsch A; Robinson HP
J. Neurophysiol., 2004



TABLE 1.Summary of statistics on RS and FS cells
Parameter Regular-Spiking Fast-Spiking P
Number of cells 20 23
Maximum firing rate, Hz 32.3 ± 7.0 61.0 ± 9.1 <0.001
Resting potential, mV –71.8 ± 3.5 –71.2 ± 4.0 —
Input resistance, MΩ 424.0 ± 189.7 357.4 ± 147.5 —
Time constant, ms 41.2 ± 12.5 29.7 ± 5.9 <0.005
Spike amplitude, mV 78.1 ± 9.0 72.8 ± 6.5 <0.05
AHP amplitude, mV 7.3 ± 2.4 17.1 ± 4.1 <0.001
1st spike width (W1), ms 1.71 ± 0.36 1.18 ± 0.17 <0.001
2nd spike width (W2), ms 2.22 ± 0.50 1.25 ± 0.18 <0.001
Adaptation index (A) 71.4 ± 4.2 56.2 ± 6.7 <0.001
Adaptation decay time constant (τa), ms 29.5 ± 9.5 54.2 ± 33.8 <0.05
Ri, MΩ 349.7 ± 165.2 229.3 ± 73.1 <0.05
τi, ms 40.2 ± 10.53 21.8 ± 9.2 <0.001
d1 0.84 ± 0.12 0.65 ± 0.13 <0.001
dss 0.57 ± 0.12 0.36 ± 0.12 <0.001
Values are means ± SD. Significant differences between the RS and FS groups are indicated in P. RS, regular spiking; FS, fast spiking; AHP, afterhyperpolarization; SS, steady state; Ri, input resistance estimated by impedance amplitude; τi time constant estimated by impedance amplitude; d1, the power parameter d of the approximation of the f–I curve by f = (aI – b)d for the 1st instantaneous firing frequency; dss, for SS firing frequency.

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 2-3 somatosensory cortex layer 2/3 regular-spiking pyramidal neuron maximum firing rate (Hz) 32.3 ± 7.0 (20) 32.3 (Hz) Data Table
Other somatosensory cortex layer 2/3 fast-spiking inhibitory interneuron maximum firing rate (Hz) 61.0 ± 9.1 (23) 61.0 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 somatosensory cortex layer 2/3 regular-spiking pyramidal neuron resting membrane potential (mV) -71.8 ± 3.5 (20) -71.8 (mV) Data Table
Other somatosensory cortex layer 2/3 fast-spiking inhibitory interneuron resting membrane potential (mV) -71.2 ± 4.0 (23) -71.2 (mV) Data Table
Neocortex pyramidal cell layer 2-3 somatosensory cortex layer 2/3 regular-spiking pyramidal neuron input resistance (MΩ) 424.0 ± 189.7 (20) 424.0 (MΩ) Data Table
Other somatosensory cortex layer 2/3 fast-spiking inhibitory interneuron input resistance (MΩ) 357.4 ± 147.5 (23) 357.4 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 somatosensory cortex layer 2/3 regular-spiking pyramidal neuron membrane time constant (ms) 41.2 ± 12.5 (20) 41.2 (ms) Data Table
Other somatosensory cortex layer 2/3 fast-spiking inhibitory interneuron membrane time constant (ms) 29.7 ± 5.9 (23) 29.7 (ms) Data Table
Neocortex pyramidal cell layer 2-3 somatosensory cortex layer 2/3 regular-spiking pyramidal neuron spike amplitude (mV) 78.1 ± 9.0 (20) 78.1 (mV) Data Table
Other somatosensory cortex layer 2/3 fast-spiking inhibitory interneuron spike amplitude (mV) 72.8 ± 6.5 (23) 72.8 (mV) Data Table
Neocortex pyramidal cell layer 2-3 somatosensory cortex layer 2/3 regular-spiking pyramidal neuron AHP amplitude (mV) 7.3 ± 2.4 (20) 7.3 (mV) Data Table
Other somatosensory cortex layer 2/3 fast-spiking inhibitory interneuron AHP amplitude (mV) 17.1 ± 4.1 (23) 17.1 (mV) Data Table
Neocortex pyramidal cell layer 2-3 somatosensory cortex layer 2/3 regular-spiking pyramidal neuron spike half-width 1.71 ± 0.36 (20) 1.71 (ms) Data Table
Other somatosensory cortex layer 2/3 fast-spiking inhibitory interneuron spike half-width 1.18 ± 0.17 (23) 1.18 (ms) Data Table
Neocortex pyramidal cell layer 2-3 somatosensory cortex layer 2/3 regular-spiking pyramidal neuron adaptation percent (1 – first/last ISI) (A) 71.4 ± 4.2 (20) 71.4 (ratio) Data Table
Other somatosensory cortex layer 2/3 fast-spiking inhibitory interneuron adaptation percent (1 – first/last ISI) (A) 56.2 ± 6.7 (23) 56.2 (ratio) Data Table