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Article: P2Y1 receptor modulation of Ca2+-activated K+ currents in medium-sized neurons from neonatal rat striatal slices.

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Coppi E; Pedata F; Gibb AJ
J. Neurophysiol., 2012


Table 1.

Fitted parameters for averaged conductance-voltage relations

2-MeSADP 2-MeSADP 2-MeSADP 2-MeSADP
+TEA +IbTX +Apamin
gmin (nS) 0.02 0.08 0.01 0.02
gmax (nS) 4.86 3.84 4.17 2.41
z 2.91 1.95 2.9 4.41
V1/2 (mV) −14.2 0.39 −1.07 −14.7

  • Values for maximum value for the voltage-dependent conductance (gmax), equivalent charge (z), and membrane potential at which 1/2 of gmax is reached (V1/2 ) obtained by fitting the 2-(Methylthio) ADP trisodium salt (2-MeSADP)-activated conductance (n = 62), tetraethylammonium (TEA)-sensitive conductance (n = 8), iberiotoxin (IbTX)-sensitive conductance (n = 12), and apamin-sensitive conductance (n = 11). gmin, minimum value for the voltage-dependent conductance.


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