Article: Differences in Na+ conductance density and Na+ channel functional properties between dopamine and GABA neurons of the rat substantia nigra.

Table 1.

Comparison showing differences in evoked action potential parameters in DA neurons and GABA neurons of the rat substantia nigra

	DA Neurons	GABA Neurons	GABA Neurons in TTX	GABA Neurons After TTX Washout
Amplitude, mV	86.7 ± 2.8 (n = 8)	107.7 ± 1.3 (n = 10; P < 0.001)	95.0 ± 1.9 (n = 10; P < 0.01)	103.5 ± 2.4 (n = 7; P < 0.05)
Duration at half-maximal amplitude, ms	1.42 ± 0.08 (n = 8)	0.98 ± 0.07 (n = 10; P < 0.01)	1.15 ± 0.10 (n = 10; P < 0.01)	1.02 ± 0.10 (n = 7; P < 0.05)
dV/dt_max, Vs⁻¹	103.7 ± 7.2 (n = 8)	320.5 ± 28.3 (n = 10; P < 0.001)	177.1 ± 14.7 (n = 10; P < 0.01)	262.8 ± 27.3 (n = 7; P < 0.05)

Numerical values are given as means ± SE and total number of recordings in parentheses. Statistical significance was tested between dopamine (DA) and GABA neurons for action potential (AP) amplitude, duration at half amplitude, and maximal rate of rise with a Wilcoxon rank sum test; between GABA neurons in control and GABA neurons in presence of TTX for the same parameters and between GABA neurons in the presence of TTX and after the washout of TTX with a Wilcoxon signed-rank test.

Inferred neuron-electrophysiology data values

Neuron Type	Ephys Prop	Extracted Value	Standardized Value	Content Source
Substantia nigra pars compacta dopaminergic cell	spike max rise slope	103.7 ± 7.2	103.7 (mV/ms)	Data Table
Substantia nigra pars reticulata interneuron GABA	spike max rise slope	320.5 ± 28.3	320.5 (mV/ms)	Data Table
Substantia nigra pars compacta dopaminergic cell	spike amplitude (mV)	86.7 ± 2.8	86.7 (mV)	Data Table
Substantia nigra pars reticulata interneuron GABA	spike amplitude (mV)	107.7 ± 1.3	107.7 (mV)	Data Table
Substantia nigra pars compacta dopaminergic cell	spike half-width (ms)	1.42 ± 0.08	1.42 (ms)	Data Table
Substantia nigra pars reticulata interneuron GABA	spike half-width (ms)	0.98 ± 0.07	0.98 (ms)	Data Table