Naïve | Control | NaV1.7 shRNA | |
---|---|---|---|
Statistical comparisons were made using one-way ANOVAs followed by Tukey's post hoc test. An asterisk denotes a significant difference between naïve and control neurons (*P < 0.01 compared to naïve and control groups). | |||
Resting membrane potential (mV) | −50.7 ± 3.07 (7) | −50.4 ± 1.45 (12) | −48.3 ± 3.61 (8) |
Threshold (mV) | −41.6 ± 1.13 (12) | −46.1 ± 0.70 (12) | −29.3 ± 2.42 (9)* |
Rheobase (pA) | 24.2 ± 2.88 (12) | 17.8 ± 3.64 (12) | 105 ± 13.23 (9)* |
Width at 0 mV (ms) | 3.7 ± 0.61 (12) | 2.3 ± 0.29 (12) | 2.8 ± 0.22 (9) |
Article: Selective silencing of Na(V)1.7 decreases excitability and conduction in vagal sensory neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Muroi Y; Ru F; Kollarik M; Canning BJ; Hughes SA; Walsh S; Sigg M; Carr MJ; Undem BJ J. Physiol. (Lond.), 2011
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Dorsal root ganglion cell | resting membrane potential (mV) | -50.7 ± 3.07 (7) | -50.7 (mV) | Data Table | |
Dorsal root ganglion cell | spike threshold (mV) | -41.6 ± 1.13 (12) | -41.6 (mV) | Data Table | |
Dorsal root ganglion cell | rheobase (pA) | 24.2 ± 2.88 (12) | 24.2 (pA) | Data Table |