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Article: Postsynaptic action of BDNF on GABAergic synaptic transmission in the superficial layers of the mouse superior colliculus.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Henneberger C; Jüttner R; Rothe T; Grantyn R
J. Neurophysiol., 2002


Table 1.

Summary of quantitative data

bdnf+/+ bdnf−/− PValue
Mean n Mean n
Basic properties
 Input resistance, MΩ 521 ± 101 22 503 ± 91 22 n.s.
 Whole cell capacitance, pF 16 ± 2 22 16 ± 4 22 n.s.
 Membrane potential, mV 44.2 ± 2.1 23 44.4 ± 1.5 30 n.s
Spontaneous action potential discharge
 Action potential frequency, s−1 5.3 ± 0.6 32 2.5 ± 0.3 21 <0.01
 Bicuculline to control ratio 1.31 ± 0.17 14 1.99 ± 0.30 11 <0.05
eIPSCs
 Average peak amplitude, pA 93 ± 9 19 178 ± 23 20 <0.01
 Variation of peak amplitude, CV 0.41 ± 0.03 19 0.40 ± 0.02 20 n.s.
 Decay time constant τ, ms 14.3 ± 1.2 19 15.8 ± 1.2 20 n.s
sIPSCs
 Average peak amplitude, pA 33 ± 2 41 46 ± 4 42 <0.001
 Decay time constant τ, ms 20.4 ± 1.7 21 22.3 ± 1.7 24 n.s.
 Frequency, s−1 0.88 ± 0.30 21 0.81 ± 0.20 24 n.s.
mIPSCs
 Average peak amplitude, pA 21.3 ± 1.9 13 33.7 ± 4.3 13 <0.05
 Time to peak (20–80%), ms 1.0 ± 0.1 13 0.9 ± 0.1 13 n.s.
 Decay time constant τ, ms 20.4 ± 1.5 13 22.7 ± 2.1 13 n.s.
 Frequency, s−1 0.11 ± 0.03 13 0.13 ± 0.04 13 n.s.
Paired-pulse ratio
 25-ms interval 1.37 ± 0.19 18 1.33 ± 0.11 18 n.s.
 50-ms interval 1.08 ± 0.11 18 1.17 ± 0.07 18 n.s
  • eIPSC, sIPSC, and mIPSC, evoked, spontaneous, and miniature inhibitory postsynaptic current.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Superior colliculus superficial layer neuron cell capacitance (pF) 16.0 ± 2.0 (22) -- Data Table
Superior colliculus superficial layer neuron resting membrane potential (mV) 44.2 ± 2.1 (22) -- Data Table
Superior colliculus superficial layer neuron firing frequency 5.3 ± 0.6 (22) -- Data Table
Superior colliculus superficial layer neuron input resistance 521.0 ± 101.0 (22) -- Data Table