Table 2.
Synaptic response properties
WT | R6/2-Presymptomatic | WT | R6/2-Symptomatic | |
---|---|---|---|---|
Maximum amplitude, mV | 24.6 ± 1.8 (7) | 24.6 ± 1.8 (17) | 20.4 ± 2.8 (11) | 22.1 ± 3.2 (4) |
Amplitude, mV 2-a | 7.9 ± 0.8 (10) | 7.7 ± 0.6 (20) | 7.1 ± 0.7 (16) | 7.7 ± 1.0 (9) |
Half amplitude duration | 9.3 ± 0.7 (10) | 10.5 ± 0.7 (14) | 9.3 ± 0.7 (14) | 10.5 ± 1.4 (9) |
Area, mV × ms | 99.7 ± 10.7 (10) | 109.6 ± 12.1 (14) | 91.0 ± 6.5 (14) | 117.6 ± 19.5 (9) |
10–90 Rise Time, mV/ms | 2.9 ± 0.2 (10) | 2.9 ± 0.2 (20) | 2.6 ± 0.2 (16) | 3.3 ± 0.3 (9)* |
Decay τ, ms | 6.1 ± 0.4 (10) | 7.4 ± 0.7 (14) | 7.2 ± 0.9 (14) | 7.4 ± 1.6 (8) |
Amplitude at 45 ms, mV | 0.52 ± 0.28 (10) | 0.54 ± 0.23 (14) | 0.19 ± 0.18 (14) | 0.99 ± 0.16 (8)2-160 |
PPF | 1.23 ± 0.05 (10) | 1.15 ± 0.08 (14)2-160 | 1.32 ± 0.05 (14) | 1.03 ± 0.05 (7)2-160 |