Article: Increased spike broadening and slow afterhyperpolarization in CA1 pyramidal cells of streptozotocin-induced diabetic rats.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Kamal A; Artola A; Biessels GJ; Gispen WH; Ramakers GM Neuroscience, 2003
Table 1Passive and active properties of CA1 pyramidal cells from STZ-diabetic and control rats
No significant differences in the RMP, Rin, τmembrane, AP amplitude and AP duration were detected between CA1 pyramidal cells from STZ-diabetic and control rats.
STZ-diabetic | Control | |
RMP (mV) | −72.65 1.14 (56) | −71.93 1.02 (53) |
Rin (MΩ) | 33.36 2.05 (30) | 32.73 1.64 (25) |
τmembrane (ms) | 8.24 0.52 (30) | 8.00 0.47 (25) |
AP amplitude (mV) | 97.43 4.62 | 91.64 2.77 |
AP duration (ms) | 1.87 0.24 | 1.80 0.21 |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Hippocampus CA1 pyramidal cell | membrane time constant (ms) | 8.0 (25) | 8.0 (ms) | Data Table | |
Hippocampus CA1 pyramidal cell | spike amplitude (mV) | 91.642 | 91.64 (mV) | Data Table | |
Hippocampus CA1 pyramidal cell | spike width (ms) | 1.8 | 1.8 (ms) | Data Table | |
Hippocampus CA1 pyramidal cell | resting membrane potential (mV) | -71.931 (53) | -71.93 (mV) | Data Table | |
Hippocampus CA1 pyramidal cell | input resistance (MΩ) | 32.731 (25) | 32.73 (MΩ) | Data Table |