CB1R+IN→GC | HICAP→GC | HIPP→GC | PV+BC→GC | |
---|---|---|---|---|
AP half-width (ms) | 1.7 ± 0.1 | 1.7 ± 0.1 | 1.9 ± 0.2 | 1.2 ± 0.1 |
CV of ISI | 0.75 ± 0.20 | 0.80 ± 0.26 | 0.54 ± 0.32 | 0.09 ± 0.01 |
Rin (MΩ) | 303 ± 13 | 343 ± 18 | 295 ± 48 | 109 ± 20 |
τm (ms) | 42.2 ± 3.2 | 45.9 ± 1.6 | 40.8 ± 5.2 | 16.5 ± 2.6 |
Latency (ms) | 3.4 ± 0.3 | 3.8 ± 0.3 | 3.7 ± 0.4 | 1.6 ± 0.2 |
20-80% rise time (ms) | 1.6 ± 0.4 | 1.8 ± 0.3 | 2.5 ± 0.1 | 0.7 ± 0.1 |
uIPSC decay τ (ms) | 19.9 ± 5.5 | 27.2 ± 5.2 | 40.7 ± 6.8 | 16.4 ± 4.4 |
Peak amplitude of uIPSC (pA)b | 12.0 ± 4.5 | 1.7 ± 0.5 | 9.2 ± 5.8 | 32.5 ± 8.9 |
Peak amplitude of uIPSC1 (pA)c | 118.0 ± 78.3 | 16.1 ± 3.5 | 14.5 ± 8.7 | 24.0 ± 9.0 |
Charge transfer per AP (pC)b | 0.18 ± 0.08 | 0.03 ± 0.01 | 0.15 ± 0.06 | 0.51 ± 0.15 |
Charge transfer per AP (pC)c | 2.03 ± 1.14 | 0.31 ± 0.08 | 0.43 ± 0.23 | 0.29 ± 0.07 |
Failure rate of uIPSCb | 0.68 ± 0.07 | 0.91 ± 0.02 | 0.59 ± 0.11 | 0.07 ± 0.05 |
Failure rate of uIPSC1c | 0.20 ± 0.05 | 0.21 ± 0.07 | 0.39 ± 0.07 | 0.17 ± 0.07 |
Multiple-pulse depressiond | 0.73 ± 0.15 | 0.68 ± 0.26 | 0.65 ± 0.05 | 0.44 ± 0.04 |
-
↵aData from rigorously confirmed CB1R+IN-to-GC (n = 5), HICAP-to-GC (n = 7), HIPP-to-GC (n = 4), and PV+BC-to-GC (n = 4) pairs.
-
↵buIPSCs were measured during the single firing mode, including failures.
-
↵cuIPSCs were measured during the burst firing mode, including failures.
-
↵dMultiple-pulse depression (25 Hz) was defined as IPSC5/IPSC1.