Article: Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Kalume F; Oakley JC; Westenbroek RE; Gile J; de la Iglesia HO; Scheuer T; Catterall WA Neurobiol. Dis., 2015
Genotype | AP threshold (mV) | AP width (ms) | AP peak voltage (mV) | Input resistance (MΩ) |
---|---|---|---|---|
WT | - 35.1 ± 1.0 | 8.5 ± 0.4 | 40.6 ± 6.0 | 75.0 ± 9.0 |
HET | - 37.7 ± 1.0 | 8.6 ± 0.7 | 35.1 ± 6.0 | 69.8 ± 11 |
KO | - 38.1 ± 1.0 | 8.6 ± 0.4 | 33.2 ± 5.0 | 71.8 ± 9.0 |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Thalamic reticular nucleus cell | Reticular Nucleus of the Thalamus GABAergic Neuron | spike threshold (mV) | -35.1 ± 1.0 | -35.1 (mV) | Data Table |
Thalamic reticular nucleus cell | Reticular Nucleus of the Thalamus GABAergic Neuron | spike width (ms) | 8.5 ± 0.4 | 8.5 (ms) | Data Table |
Thalamic reticular nucleus cell | Reticular Nucleus of the Thalamus GABAergic Neuron | spike peak (mV) | 40.6 ± 6.0 | 40.6 (mV) | Data Table |
Thalamic reticular nucleus cell | Reticular Nucleus of the Thalamus GABAergic Neuron | input resistance (MΩ) | 75.0 ± 9.0 | 75.0 (MΩ) | Data Table |